{"id":"W4387082132","doi":"10.1016/j.jtct.2023.09.017","title":"Incidence and Impact of Fungal Infections in Post-Transplantation Cyclophosphamide-Based Graft-versus-Host Disease Prophylaxis and Haploidentical Hematopoietic Cell Transplantation: A Center for International Blood and Marrow Transplant Research Analysis","year":2023,"lang":"en","type":"article","venue":"Transplantation and Cellular Therapy","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"National Institute of Environmental Health Sciences; National Institute of Allergy and Infectious Diseases; Gilead Sciences; National Cancer Institute; bluebird bio; Kiadis Pharma; Astellas Pharma; Adaptive Biotechnologies; Incyte; National Heart, Lung, and Blood Institute; Actinium Pharmaceuticals; CareDx; Office of Naval Research; Jazz Pharmaceuticals; Atara Biotherapeutics; Bristol-Myers Squibb; CSL Behring; BeiGene; HistoGenetics; Gateway for Cancer Research; GlaxoSmithKline; Health Resources and Services Administration; Astellas Pharma US; Amgen","keywords":"Medicine; Cumulative incidence; Internal medicine; Transplantation; Incidence (geometry); Proportional hazards model; Graft-versus-host disease; Hematopoietic stem cell transplantation; Cyclophosphamide; Immunology; Calcineurin; Gastroenterology; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009283557,0.0002242076,0.0003610618,0.0007253299,0.0003239111,0.0007015363,0.0004237052,0.0004995876,0.001974167],"category_scores_gemma":[0.00232064,0.0001855952,0.000603823,0.0009598672,0.0002813127,0.0004403357,0.0003697933,0.0007128175,0.0001606748],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005561011,"about_ca_system_score_gemma":0.0006822915,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003189202,"about_ca_topic_score_gemma":0.003969933,"domain_scores_codex":[0.9987459,0.0004746422,0.00011156,0.0002033427,0.0002319522,0.0002325974],"domain_scores_gemma":[0.9975197,0.0007369567,0.0009507615,0.0001414898,0.000213111,0.0004380354],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001883926,0.0002288672,0.9916053,0.00001674659,0.0001145085,0.0001317975,0.00004081424,0.0001250805,0.0003328635,0.00005738598,0.0001572939,0.00530545],"study_design_scores_gemma":[0.00001528051,0.0004246194,0.9987732,0.000004030505,0.00005567461,0.0002236259,0.00008383636,0.0001824576,0.0001123694,0.00001696398,0.0001040471,0.000003860619],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984944,0.0006195958,0.000069505,0.00003083168,0.000006159207,0.000007634319,0.0002424448,0.000003563007,0.0005259138],"genre_scores_gemma":[0.9995731,0.0001311871,0.00003163227,0.0000148238,0.000009269225,0.000003487288,0.0001257504,0.000001623682,0.0001090991],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003189202,"threshold_uncertainty_score":0.006604254,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02455374356129006,"score_gpt":0.3286458289797422,"score_spread":0.3040920854184522,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}