{"id":"W4387082132","doi":"10.1016/j.jtct.2023.09.017","title":"Incidence and Impact of Fungal Infections in Post-Transplantation Cyclophosphamide-Based Graft-versus-Host Disease Prophylaxis and Haploidentical Hematopoietic Cell Transplantation: A Center for International Blood and Marrow Transplant Research Analysis","year":2023,"lang":"en","type":"article","venue":"Transplantation and Cellular Therapy","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"National Institute of Environmental Health Sciences; National Institute of Allergy and Infectious Diseases; Gilead Sciences; National Cancer Institute; bluebird bio; Kiadis Pharma; Astellas Pharma; Adaptive Biotechnologies; Incyte; National Heart, Lung, and Blood Institute; Actinium Pharmaceuticals; CareDx; Office of Naval Research; Jazz Pharmaceuticals; Atara Biotherapeutics; Bristol-Myers Squibb; CSL Behring; BeiGene; HistoGenetics; Gateway for Cancer Research; GlaxoSmithKline; Health Resources and Services Administration; Astellas Pharma US; Amgen","keywords":"Medicine; Cumulative incidence; Internal medicine; Transplantation; Incidence (geometry); Proportional hazards model; Graft-versus-host disease; Hematopoietic stem cell transplantation; Cyclophosphamide; Immunology; Calcineurin; Gastroenterology; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006226692,0.0002228177,0.0003640048,0.0006558236,0.0001652401,0.00005748988,0.00006017051,0.0001224766,0.00003727304],"category_scores_gemma":[0.00003352045,0.0001956041,0.0001570037,0.0006555179,0.0002936794,0.0002033339,0.000004404195,0.0002154732,9.416171e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002731307,"about_ca_system_score_gemma":0.000121627,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002586195,"about_ca_topic_score_gemma":0.0006039464,"domain_scores_codex":[0.9981924,0.0001559255,0.000445781,0.0004935269,0.0004190834,0.0002932381],"domain_scores_gemma":[0.9987674,0.0004812416,0.00006991626,0.0001433584,0.0003044584,0.0002336667],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01482201,0.0003984411,0.9183576,0.001731284,0.0003158481,0.0002150613,0.00390861,0.00004544751,0.0596183,0.00009752189,0.000001660677,0.0004881814],"study_design_scores_gemma":[0.009829938,0.001135875,0.9756994,0.0002186338,0.0007983213,0.0000311501,0.0002966097,0.001054891,0.01063316,0.00009939126,0.000003818989,0.0001987888],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944475,0.0009773672,0.002545717,0.0002304046,0.00006199392,0.0008845878,0.0007894658,0.00003619075,0.0000267716],"genre_scores_gemma":[0.9799166,0.01868616,0.0001326156,0.00003170697,0.0000261466,0.00007954295,0.001075775,0.00002090297,0.00003052353],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05734179,"threshold_uncertainty_score":0.7976505,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02455374356129006,"score_gpt":0.3286458289797422,"score_spread":0.3040920854184522,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}