{"id":"W4387092622","doi":"10.1371/journal.pone.0292157","title":"Effects of Heparan sulfate acetyl-CoA: Alpha-glucosaminide N-acetyltransferase (HGSNAT) inactivation on the structure and function of epithelial and immune cells of the testis and epididymis and sperm parameters in adult mice","year":2023,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Proteoglycans and glycosaminoglycans research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Queen's University; McGill University","funders":"Canadian Glycomics Network; Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; McGill University","keywords":"Epididymis; Heparan sulfate; Biology; Cell biology; Lysosome; Sertoli cell; Seminiferous tubule; Basement membrane; Sperm; Epithelium; Endocrinology; Molecular biology; Internal medicine; Glycosaminoglycan; Biochemistry; Spermatogenesis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001955885,0.0006314893,0.0003341594,0.0004821281,0.0001904858,0.0002800756,0.0003109966,0.0005927837,0.001675449],"category_scores_gemma":[0.0001464605,0.0002802885,0.0004883575,0.0002124814,0.0004712577,0.0002838709,0.0002680335,0.0009354813,0.0002577777],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002748999,"about_ca_system_score_gemma":0.0002913617,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001244166,"about_ca_topic_score_gemma":0.001685334,"domain_scores_codex":[0.9997316,0.00003866715,0.00003227645,0.00008430819,0.00005055233,0.0000625579],"domain_scores_gemma":[0.9996387,0.00003610314,0.0001094066,0.00002945121,0.00002664557,0.0001596696],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008758315,0.0001842486,0.0007395927,0.00005060169,0.0000234975,0.00018608,0.00003934337,0.0001193221,0.9960992,0.0001380055,0.00006858491,0.001475656],"study_design_scores_gemma":[0.00008945705,0.002399365,0.02029529,0.00001578651,0.0001014333,0.0005003206,0.00009822125,0.001215664,0.9732381,0.000135031,0.00189314,0.00001814754],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966707,0.001107851,0.000788102,0.00008624329,0.0000308677,0.00002690013,0.0005472855,0.0001066306,0.0006355647],"genre_scores_gemma":[0.9917133,0.0009569742,0.00102572,0.00009776228,0.00001523418,0.00005471205,0.0008955601,0.00004314854,0.005197625],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001675449,"threshold_uncertainty_score":0.005604982,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01206927478956238,"score_gpt":0.2110914108433791,"score_spread":0.1990221360538167,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}