{"id":"W4387096270","doi":"10.7554/elife.90274.1","title":"Simultaneous Recognition of Multiple Signals in Bacterial Outer Membrane Proteins Enhance Assembly and Maintain Membrane Integrity","year":2023,"lang":"en","type":"preprint","venue":"","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Impact","funders":"Japan Society for the Promotion of Science","keywords":"Membrane integrity; Membrane; Bacterial outer membrane; Structural integrity; Membrane protein; Cell biology; Chemistry; Biophysics; Computer science; Biology; Biochemistry; Engineering; Escherichia coli; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001400039,0.0003033642,0.0002726626,0.0001313979,0.0001195563,0.0003925427,0.0001468347,0.0002797905,0.002561641],"category_scores_gemma":[0.0001679265,0.0001128659,0.0001867471,0.0001047965,0.000212527,0.0002448338,0.0003838926,0.0004274047,0.001015557],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002420703,"about_ca_system_score_gemma":0.0001343043,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001325002,"about_ca_topic_score_gemma":0.0001476822,"domain_scores_codex":[0.9998671,0.00001473715,0.000006140238,0.00002805901,0.00004436049,0.00003961357],"domain_scores_gemma":[0.9998686,0.00002522014,0.00002538514,0.00001492094,0.00001964184,0.00004620967],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008644926,0.00001767905,0.0001094094,0.00001934795,0.000001779556,0.00002407262,0.000002940355,0.00005505299,0.9989195,0.0001380091,0.00005076495,0.0005749661],"study_design_scores_gemma":[0.00001408513,0.00007450075,0.001100388,0.000002639146,0.000003204832,0.00008313513,0.00001114793,0.001596527,0.9959934,0.0001155977,0.001002948,0.000002384194],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9911226,0.0009394794,0.005212864,0.0001491232,0.00008860351,0.0000124356,0.0001071405,0.000110591,0.002257129],"genre_scores_gemma":[0.9927758,0.0001790138,0.003366885,0.00006362896,0.0000171399,0.000008636919,0.0001332588,0.00003394586,0.003421685],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002561641,"threshold_uncertainty_score":0.008569479,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02189301125856323,"score_gpt":0.2652103941355595,"score_spread":0.2433173828769962,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}