{"id":"W4387101522","doi":"10.3390/genes14101879","title":"Tissue-Specific Tumour Suppressor and Oncogenic Activities of the Polycomb-like Protein MTF2","year":2023,"lang":"en","type":"review","venue":"Genes","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"PRC2; Polycomb-group proteins; Chromatin; Biology; Histone H3; Epigenetics; Cell biology; Chromatin remodeling; Transcription factor; Gene silencing; Histone; Genetics; Gene; Repressor","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001077234,0.000253336,0.0002675086,0.0003443712,0.0001122369,0.0003423001,0.0002056541,0.0002497125,0.0008873204],"category_scores_gemma":[0.0001615586,0.00007790914,0.0001616959,0.0003395306,0.0002137153,0.000260933,0.0002106877,0.0003600758,0.0004354597],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003174485,"about_ca_system_score_gemma":0.0002803317,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004746981,"about_ca_topic_score_gemma":0.0007441336,"domain_scores_codex":[0.9999141,0.00001300852,0.00001001571,0.00001733551,0.00003299366,0.00001260732],"domain_scores_gemma":[0.999967,0.000007575683,0.000007980352,0.000002184878,0.000009509913,0.000005699892],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003037306,0.00003617783,0.001637181,0.008288998,0.0001129459,0.00200326,0.0001891808,0.0009951603,0.2837858,0.02073223,0.02205655,0.6598588],"study_design_scores_gemma":[0.00001336582,0.0001169489,0.005421909,0.0002617065,0.00008009955,0.005532866,0.00004112811,0.0003855963,0.06598357,0.002771281,0.9193714,0.00002019885],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0116846,0.9754022,0.002852832,0.0008549882,0.0004919462,0.00001081424,0.0001549741,0.00005523397,0.008492437],"genre_scores_gemma":[0.1093564,0.8748512,0.001636227,0.0005221502,0.0008915136,0.00003218118,0.0003512102,0.00001965889,0.01233941],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.0008873204,"threshold_uncertainty_score":0.002968431,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04518949937553444,"score_gpt":0.3138574551259634,"score_spread":0.2686679557504289,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}