{"id":"W4387103392","doi":"10.1002/mco2.376","title":"Intratumor microbiome: selective colonization in the tumor microenvironment and a vital regulator of tumor biology","year":2023,"lang":"en","type":"review","venue":"MedComm","topic":"Cancer Research and Treatments","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"CAE (Canada)","funders":"National Natural Science Foundation of China; Basic and Applied Basic Research Foundation of Guangdong Province; Guangzhou Medical University","keywords":"Microbiome; Regulator; Colonization; Master regulator; Tumor microenvironment; Biology; Computational biology; Cancer research; Microbiology; Tumor cells; Bioinformatics; Genetics; Transcription factor; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003707973,0.0006229289,0.0009028638,0.001640433,0.0003574684,0.001291103,0.0004856074,0.0011267,0.002907931],"category_scores_gemma":[0.0005969526,0.0001740818,0.0003824897,0.001304492,0.0006850606,0.001264086,0.0008139109,0.001498792,0.001317916],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006753876,"about_ca_system_score_gemma":0.001167928,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008014322,"about_ca_topic_score_gemma":0.001364736,"domain_scores_codex":[0.9997875,0.00004675847,0.00001829662,0.00004026379,0.00007998131,0.00002713512],"domain_scores_gemma":[0.9997867,0.00009710281,0.00002826861,0.00000890507,0.00005290678,0.00002615462],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007124196,0.00004621589,0.0004516711,0.01329972,0.00007574719,0.0003135533,0.0001257669,0.000325159,0.005537121,0.0150123,0.05350981,0.9112318],"study_design_scores_gemma":[0.000005202049,0.00005026173,0.0008137168,0.001855512,0.00004176598,0.001245028,0.00007831444,0.00008297204,0.0007397934,0.003408826,0.9916619,0.00001677539],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002817819,0.9952017,0.0004107063,0.0009344895,0.0007330955,0.000006076671,0.00003395801,0.00001703798,0.002381219],"genre_scores_gemma":[0.002217153,0.9950255,0.0003153733,0.000490253,0.0004259255,0.000008800243,0.00004644469,0.000003408805,0.001467149],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002907931,"threshold_uncertainty_score":0.009728014,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02023049947445825,"score_gpt":0.3234020304945576,"score_spread":0.3031715310200994,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}