{"id":"W4387109533","doi":"10.4236/oji.2023.133005","title":"RP215 and GHR106 Monoclonal Antibodies and Potential Therapeutic Applications","year":2023,"lang":"en","type":"article","venue":"Open Journal of Immunology","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Monoclonal antibody; Antibody; Cancer; Cancer cell; Epitope; Cancer research; Biology; Cytotoxic T cell; Cancer immunotherapy; Humanized antibody; Immunotherapy; In vitro; Immunology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003783079,0.0001069908,0.0003506177,0.0002105308,0.0001743461,0.00006370286,0.0002159235,0.00007360129,0.0001243607],"category_scores_gemma":[0.00002765212,0.00007700061,0.00005896765,0.0001776085,0.0003317219,0.0001323309,0.0003296888,0.0003157559,0.00003938143],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001280531,"about_ca_system_score_gemma":0.0001145663,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003748757,"about_ca_topic_score_gemma":0.000002494667,"domain_scores_codex":[0.9990824,0.00006937831,0.0003054126,0.0001395473,0.0001695501,0.0002336593],"domain_scores_gemma":[0.9993654,0.0001115561,0.0001269925,0.0001205886,0.0001694427,0.000106046],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.004053135,0.0003467407,0.09598698,0.0001946731,0.002162249,0.0009878863,0.0009212387,0.000007774711,0.3892757,0.0104461,0.004141536,0.491476],"study_design_scores_gemma":[0.003457961,0.00173517,0.816541,0.000110085,0.0001649682,0.01014616,0.0009436589,0.0001901186,0.003443855,0.01050592,0.1525358,0.0002252525],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9765148,0.01013162,0.0001255398,0.01106084,0.0001081264,0.000300601,0.00001035854,0.00001043661,0.001737682],"genre_scores_gemma":[0.9804677,0.01385613,0.001090885,0.0003229841,0.0001767735,0.00001274212,0.00001218572,0.00001549175,0.004045047],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7205541,"threshold_uncertainty_score":0.3139994,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03666376136627258,"score_gpt":0.3569137287912009,"score_spread":0.3202499674249283,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}