{"id":"W4387114927","doi":"10.1111/nan.12939","title":"Brain pathology of lissencephaly type 2 with an <i>ISPD</i> pathogenic variant","year":2023,"lang":"en","type":"article","venue":"Neuropathology and Applied Neurobiology","topic":"RNA regulation and disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Health Sciences Centre; University of Toronto; Mount Sinai Hospital; Sunnybrook Health Science Centre","funders":"","keywords":"Medical laboratory; Neuropathology; Medicine; Library science; Family medicine; Pathology; Computer science; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002593797,0.001664244,0.0004120935,0.001364074,0.0006903178,0.0005789293,0.0005432415,0.001267389,0.004243511],"category_scores_gemma":[0.0005238773,0.0004020479,0.0005731201,0.0006689401,0.001313769,0.0003802121,0.0005061277,0.0008202271,0.0007429792],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003858445,"about_ca_system_score_gemma":0.000362117,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002995786,"about_ca_topic_score_gemma":0.002011101,"domain_scores_codex":[0.9998345,0.0000198363,0.00002606891,0.00004512782,0.00003597609,0.00003833903],"domain_scores_gemma":[0.9996501,0.00008436992,0.0001394135,0.00002050269,0.00003333694,0.0000721672],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.001049711,0.0001394536,0.02378408,0.000129237,0.0001891322,0.8355204,0.0005319677,0.0004115463,0.1315086,0.0009021787,0.001237502,0.004596105],"study_design_scores_gemma":[0.0001603421,0.0007192755,0.1406527,0.0000679758,0.0003908717,0.8163666,0.0006289184,0.001751011,0.03352813,0.002003914,0.003669523,0.00006084033],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9917943,0.0005188736,0.0009425063,0.0004642369,0.00009009527,0.0000297996,0.000398874,0.000105168,0.005656135],"genre_scores_gemma":[0.9979235,0.0001952921,0.0006104737,0.0001327674,0.00007649381,0.000009576634,0.0002005016,0.00002721809,0.0008241183],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004243511,"threshold_uncertainty_score":0.01419598,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008800851308799939,"score_gpt":0.2315151628519209,"score_spread":0.222714311543121,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}