{"id":"W4387117263","doi":"10.3389/fnins.2023.1295344","title":"Editorial: Prodromal stage of neurodegenerative proteinopathies: from bench to bedside","year":2023,"lang":"en","type":"editorial","venue":"Frontiers in Neuroscience","topic":"Neurological diseases and metabolism","field":"Neuroscience","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Douglas Mental Health University Institute; Toronto Western Hospital; University of Toronto","funders":"","keywords":"Bench to bedside; Neuroscience; Prodromal Stage; Medicine; Stage (stratigraphy); Psychology; Medical physics; Biology; Cognitive impairment; Cognition","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00459714,0.004515013,0.003756015,0.00324414,0.002622409,0.004839474,0.003011355,0.01115988,0.02345852],"category_scores_gemma":[0.01580305,0.0009577638,0.002610397,0.0009854157,0.001782982,0.004603337,0.001555088,0.01298811,0.01907461],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002076653,"about_ca_system_score_gemma":0.001940917,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009117328,"about_ca_topic_score_gemma":0.002529419,"domain_scores_codex":[0.9976258,0.0003806758,0.0003520293,0.0003736373,0.001069072,0.0001988854],"domain_scores_gemma":[0.9893395,0.003407929,0.0008190292,0.0002573989,0.003818554,0.00235738],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004716493,0.00000876051,0.00001879124,0.0001355995,0.000009754126,0.00009901162,0.000006001794,0.00001824355,0.00005035099,0.0001253468,0.9962065,0.003274449],"study_design_scores_gemma":[0.0001179509,0.00004759151,0.0003223511,0.000565281,0.00006225386,0.0006775836,0.00004293037,0.0002067945,0.0002057465,0.001407208,0.9963142,0.00003005985],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"editorial","genre_gemma":"editorial","genre_scores_codex":[0.00003449048,0.003134528,0.0001076706,0.01839999,0.9771097,0.00001830204,0.00006884744,0.0000623793,0.001064119],"genre_scores_gemma":[0.0003335556,0.002658339,0.00007741503,0.01226595,0.9779845,0.00001859143,0.0000427125,0.00003097708,0.00658813],"genre_candidate":"editorial","genre_consensus":"editorial","teacher_disagreement_score":0.02345852,"threshold_uncertainty_score":0.07847655,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02104205249720552,"score_gpt":0.2809626868405447,"score_spread":0.2599206343433391,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}