{"id":"W4387128991","doi":"10.1007/s12325-023-02666-z","title":"Efficacy and Safety of Single-Pill Combination of Rosuvastatin and Ezetimibe in Chinese Patients with Primary Hypercholesterolemia Inadequately Controlled by Statin Treatment (ROZEL): A Randomized, Double-Blind, Double Dummy, Active-Controlled Phase 3 Clinical Trial","year":2023,"lang":"en","type":"article","venue":"Advances in Therapy","topic":"Lipoproteins and Cardiovascular Health","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sanofi (Canada)","funders":"","keywords":"Medicine; Rosuvastatin; Statin; Double blind; Ezetimibe; Randomized controlled trial; Internal medicine; Pill; Simvastatin; Single blind; Atorvastatin; Rheumatology; Pharmacology; Alternative medicine; Placebo","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002020933,0.001326654,0.003661366,0.0003804125,0.0004512609,0.0007244118,0.0008312205,0.001492946,0.003408324],"category_scores_gemma":[0.001318838,0.0006448415,0.002044964,0.0003968891,0.0009376191,0.0006970656,0.0003627668,0.00171624,0.0005760212],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006592218,"about_ca_system_score_gemma":0.001558877,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009426653,"about_ca_topic_score_gemma":0.002415043,"domain_scores_codex":[0.9993452,0.0002884506,0.00006357096,0.0001365853,0.00007280611,0.00009335054],"domain_scores_gemma":[0.9990857,0.0001611974,0.0002461697,0.00008809796,0.00007149749,0.0003474013],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9651856,0.01154003,0.002462687,0.0005386623,0.001288685,0.00004909946,0.0000658745,0.0001622463,0.004309736,0.00004141871,0.0003700527,0.01398589],"study_design_scores_gemma":[0.8915365,0.101088,0.005511859,0.00001513072,0.0007621269,0.00003788206,0.00002184162,0.0003383497,0.0004436244,0.00003614914,0.0001911883,0.00001745061],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971655,0.001079241,0.000163398,0.0001836662,0.00009034638,0.0008027611,0.0001901615,0.00003566774,0.0002893809],"genre_scores_gemma":[0.9955844,0.0007676024,0.0008039568,0.0004722841,0.0001537316,0.001242035,0.0003834669,0.000006185458,0.0005864094],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003661366,"threshold_uncertainty_score":0.01140195,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0329011302102163,"score_gpt":0.3614932351858793,"score_spread":0.328592104975663,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}