{"id":"W4387135672","doi":"10.1136/ijgc-2023-esgo.16","title":"#540 Safety of dostarlimab in combination with chemotherapy in patients with primary advanced or recurrent endometrial cancer in a phase 3, randomized, placebo-controlled trial (ENGOT-EN6-NSGO/GOG-3031/RUBY)","year":2023,"lang":"en","type":"article","venue":"International Journal of Gynecological Cancer","topic":"Endometrial and Cervical Cancer Treatments","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University Health Centre","funders":"","keywords":"Carboplatin; Discontinuation; Medicine; Placebo; Paclitaxel; Adverse effect; Internal medicine; Chemotherapy; Tolerability; Surgery; Oncology; Cisplatin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009942491,0.001111056,0.002449314,0.0003611807,0.0003603291,0.0007617119,0.0005970866,0.001232732,0.01208974],"category_scores_gemma":[0.0008136053,0.0005372528,0.001761657,0.0003040681,0.0008695695,0.0007375006,0.0002872917,0.002723094,0.001562954],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005024722,"about_ca_system_score_gemma":0.0007905106,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009578089,"about_ca_topic_score_gemma":0.002701919,"domain_scores_codex":[0.9996765,0.0001648925,0.00001963496,0.00006198938,0.00002235452,0.000054595],"domain_scores_gemma":[0.999679,0.00007798793,0.0000763983,0.00002154531,0.00002590284,0.0001192954],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9386127,0.004791048,0.0008830042,0.001400177,0.001660896,0.00005096825,0.00004692076,0.0004729753,0.006731294,0.0002065744,0.002727163,0.04241636],"study_design_scores_gemma":[0.9128639,0.0825628,0.002049036,0.00005470633,0.0004892267,0.00003063238,0.00002011718,0.000347544,0.0004170711,0.0001043177,0.001046806,0.00001383106],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9686442,0.01439114,0.0009245162,0.002041855,0.001357463,0.003534927,0.002661443,0.000327935,0.006116463],"genre_scores_gemma":[0.9764139,0.006242376,0.001885667,0.002379701,0.000708478,0.002512049,0.002452042,0.0000567774,0.007348985],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01208974,"threshold_uncertainty_score":0.0404442,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01821743701331754,"score_gpt":0.3339632427409536,"score_spread":0.3157458057276361,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}