{"id":"W4387149313","doi":"10.3389/fnhum.2023.1208273","title":"Elevated biomarkers of neural injury in older adults following head-down bed rest: links to cardio-postural deconditioning with spaceflight and aging","year":2023,"lang":"en","type":"article","venue":"Frontiers in Human Neuroscience","topic":"Spaceflight effects on biology","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"Canadian Institutes of Health Research","keywords":"Deconditioning; Spaceflight; Bed rest; Physical medicine and rehabilitation; Head-Down Tilt; Medicine; Rest (music); Physical therapy; Cardiology; Internal medicine; Engineering","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008059642,0.0004539813,0.0004122329,0.0004735441,0.0001985631,0.000462113,0.0002999913,0.0003900139,0.0008635963],"category_scores_gemma":[0.001784146,0.0001317675,0.0002671237,0.0005782152,0.0001727214,0.0002272415,0.0003289463,0.0002782237,0.0001239573],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001362242,"about_ca_system_score_gemma":0.0001929615,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001424076,"about_ca_topic_score_gemma":0.002168301,"domain_scores_codex":[0.9996879,0.00009801052,0.00004545962,0.00006203711,0.00006558457,0.00004108897],"domain_scores_gemma":[0.9985256,0.0002009098,0.0009465264,0.00006332394,0.0001429907,0.0001207264],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001941451,0.0001277161,0.9882156,0.0001508742,0.0002122202,0.00008095433,0.0001021764,0.00006589956,0.002195993,0.00001241451,0.00008173481,0.006813015],"study_design_scores_gemma":[0.000006400619,0.000293049,0.9992862,0.000008088919,0.00004423171,0.00006672385,0.00002723169,0.00007148022,0.0001298372,0.00001176557,0.00005314415,0.000001754646],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966205,0.002416981,0.0002637138,0.0000417474,0.000009772149,0.00002329465,0.0003289486,0.000007215687,0.000287867],"genre_scores_gemma":[0.9988262,0.0004548853,0.0002762751,0.00002632745,0.0000177388,0.00002781698,0.0002508746,0.000001097382,0.0001188232],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001424076,"threshold_uncertainty_score":0.004262388,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009882993198232643,"score_gpt":0.2890082645339961,"score_spread":0.2791252713357635,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}