{"id":"W4387157798","doi":"10.1002/bit.28557","title":"Bioprocess development for cord blood mesenchymal stromal cells on microcarriers in Vertical‐Wheel bioreactors","year":2023,"lang":"en","type":"article","venue":"Biotechnology and Bioengineering","topic":"Mesenchymal stem cell research","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph; University of Calgary","funders":"Natural Sciences and Engineering Research Council of Canada; Ontario Agri-Food Innovation Alliance","keywords":"Microcarrier; Bioreactor; Mesenchymal stem cell; Bioprocess; Stromal cell; Cell; Laboratory flask; Biomedical engineering; Cell biology; Platelet lysate; Chemistry; Biology; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002447113,0.000202152,0.0002914372,0.000552324,0.00007002096,0.00001329726,0.0001305264,0.0003904385,0.00001027473],"category_scores_gemma":[0.0000990527,0.0001753987,0.00004200156,0.0007236631,0.0001677103,0.00002777879,0.0000976537,0.0003534639,0.00002438078],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006993534,"about_ca_system_score_gemma":0.000068443,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001158059,"about_ca_topic_score_gemma":0.000008847874,"domain_scores_codex":[0.9985445,0.000007065515,0.000259987,0.0004081059,0.0001695528,0.0006107566],"domain_scores_gemma":[0.999522,0.00009185472,0.00001863022,0.0001907947,0.00002671186,0.0001499708],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002500566,0.00009968636,0.004394228,0.0003666681,0.0000877232,0.0001734992,0.00005097222,0.00001481431,0.9836643,0.0004978817,0.00007097731,0.01032913],"study_design_scores_gemma":[0.001327055,0.0007440185,0.008955961,0.0001546941,0.00002678208,0.0000410572,0.0001687133,0.001051407,0.981811,0.00001088762,0.00550468,0.00020369],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973599,0.0001953326,0.0002899709,0.001154141,0.0001303115,0.0005083692,0.000009647366,0.0002985788,0.00005375818],"genre_scores_gemma":[0.9974462,0.0001379025,0.002078495,0.00003349077,0.00003675892,0.00007049672,0.00002292872,0.0000282278,0.0001454861],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01012544,"threshold_uncertainty_score":0.715255,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02568547200101838,"score_gpt":0.2801630600475764,"score_spread":0.254477588046558,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}