{"id":"W4387160309","doi":"10.1016/j.ijrobp.2023.06.1888","title":"Stereotactic Boost and Short-Course Radiotherapy for p16-Associated Oropharynx Cancer (SHORT-OPC): First Planned Interim Safety Analysis from a Randomized Phase II Trial","year":2023,"lang":"en","type":"article","venue":"International Journal of Radiation Oncology*Biology*Physics","topic":"Head and Neck Cancer Studies","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"","keywords":"Interim analysis; Interim; Radiation therapy; Medicine; Randomized controlled trial; Oncology; Surgery; Geography","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002434578,0.001417098,0.002454807,0.0003492336,0.0003883829,0.001081476,0.0009808153,0.001158233,0.006457708],"category_scores_gemma":[0.001516488,0.0005016676,0.002442028,0.0004936589,0.001193309,0.001069201,0.0004390506,0.002614332,0.000784201],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009820575,"about_ca_system_score_gemma":0.002123732,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001409318,"about_ca_topic_score_gemma":0.00322263,"domain_scores_codex":[0.999226,0.0003862786,0.00004102668,0.0001219602,0.00007297786,0.0001517974],"domain_scores_gemma":[0.9985757,0.0003698819,0.0002979493,0.0001838253,0.00008410837,0.0004885252],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9430322,0.007976652,0.00146361,0.0004872186,0.001205693,0.00003796157,0.0001118381,0.001005228,0.004716797,0.0001581091,0.001184574,0.03862008],"study_design_scores_gemma":[0.7673154,0.2228694,0.005375041,0.00003793721,0.0009744504,0.00007360257,0.00005299509,0.0006827143,0.001204204,0.0003432662,0.001049079,0.00002200801],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9923784,0.002407049,0.000810193,0.0002622539,0.0001710575,0.001647842,0.0008693138,0.00008745629,0.001366505],"genre_scores_gemma":[0.9877159,0.002218488,0.002093046,0.000710741,0.0002060454,0.002237858,0.00195566,0.00005495883,0.002807266],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006457708,"threshold_uncertainty_score":0.02160323,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04160159377398531,"score_gpt":0.4059359838098138,"score_spread":0.3643343900358285,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}