{"id":"W4387217092","doi":"10.1038/s41598-023-43390-6","title":"Innate immune dysregulation in multisystem inflammatory syndrome in children (MIS-C)","year":2023,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Kawasaki Disease and Coronary Complications","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Trinity College","funders":"","keywords":"Immune system; Immunology; CD8; Medicine; CD3; Inflammation; Flow cytometry; Tumor necrosis factor alpha; CD19; Basal (medicine); Inflammasome; Innate immune system; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002368039,0.0004637086,0.0004081326,0.0006976065,0.0003945392,0.0003494105,0.0001652535,0.0003851932,0.002025582],"category_scores_gemma":[0.0005020325,0.0001261927,0.000333722,0.0005076823,0.0003589316,0.0002869545,0.0005167701,0.0003483048,0.0001907879],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003756321,"about_ca_system_score_gemma":0.0003147235,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001450396,"about_ca_topic_score_gemma":0.001330013,"domain_scores_codex":[0.9997767,0.00003313967,0.00002843027,0.00006913602,0.00004047178,0.00005207023],"domain_scores_gemma":[0.9995541,0.00005635675,0.0002041339,0.00001541106,0.00004591416,0.0001241036],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0008799038,0.00008585333,0.9738298,0.0002501639,0.00006873738,0.004660617,0.0003418411,0.00012952,0.01201509,0.000113449,0.0002960013,0.007328914],"study_design_scores_gemma":[0.00001083619,0.0004626097,0.9841315,0.00004262966,0.00003036822,0.01345432,0.0003000829,0.00009196824,0.0008537037,0.000038305,0.0005779203,0.000005754306],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980584,0.001049482,0.0001254188,0.00003393346,0.000008840201,0.00001268586,0.0003073846,0.000007355328,0.0003965449],"genre_scores_gemma":[0.9990053,0.0003271375,0.0002316695,0.00002328224,0.00001021609,0.00001420828,0.0002630412,0.000001652755,0.0001234625],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002025582,"threshold_uncertainty_score":0.006776214,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01123831221154044,"score_gpt":0.2547556230986486,"score_spread":0.2435173108871082,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}