{"id":"W4387265159","doi":"10.3390/nu15194245","title":"Cancer Metabolism as a Therapeutic Target and Review of Interventions","year":2023,"lang":"en","type":"review","venue":"Nutrients","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Warburg effect; Cancer; Anaerobic glycolysis; Cancer cell; Glycolysis; Medicine; Cell metabolism; Anaerobic exercise; Reprogramming; Bioinformatics; Cellular metabolism; Biology; Cancer research; Metabolism; Cell; Physiology; Internal medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000471505,0.000806944,0.00123544,0.002535318,0.0003201255,0.001061559,0.0008995484,0.001093272,0.007699763],"category_scores_gemma":[0.001088728,0.0002639757,0.0007201864,0.00199763,0.0003424823,0.00102627,0.0006883341,0.001958559,0.002555416],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007302925,"about_ca_system_score_gemma":0.001244178,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001096615,"about_ca_topic_score_gemma":0.001968274,"domain_scores_codex":[0.9997981,0.0000407531,0.00003102326,0.0000409119,0.00006841555,0.00002088006],"domain_scores_gemma":[0.9996399,0.0002079753,0.00004301972,0.0000102695,0.00007431277,0.0000244834],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009312505,0.00009337352,0.00009808698,0.02944714,0.0001045978,0.0001436724,0.00005144522,0.0004292617,0.001005604,0.004708123,0.04765837,0.9161671],"study_design_scores_gemma":[0.00001534826,0.00007700112,0.0004879596,0.01125105,0.0001434225,0.0007192338,0.0000442295,0.00009163359,0.000260485,0.002312836,0.9845816,0.00001514612],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006243271,0.998109,0.0001002592,0.0003110403,0.0003286415,0.000005297203,0.00002639439,0.000007482354,0.00104942],"genre_scores_gemma":[0.0003459193,0.9985278,0.0001475721,0.0002030313,0.000186274,0.000008125061,0.00003562309,0.00000189581,0.0005437971],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.007699763,"threshold_uncertainty_score":0.02575827,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05914473516319648,"score_gpt":0.3909167132889032,"score_spread":0.3317719781257067,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}