{"id":"W4387296715","doi":"10.1001/jama.2023.17002","title":"Estimated Glomerular Filtration Rate, Albuminuria, and Adverse Outcomes","year":2023,"lang":"en","type":"review","venue":"JAMA","topic":"Chronic Kidney Disease and Diabetes","field":"Medicine","cited_by":315,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; University of Calgary; University of British Columbia","funders":"NHLBI Division of Intramural Research; National Heart, Lung, and Blood Institute; School of Medicine, Tokai University; National Health and Medical Research Council; Medical Research Council; Clinical and Translational Science Collaborative of Cleveland, School of Medicine, Case Western Reserve University; Johns Hopkins Bloomberg School of Public Health; Perelman School of Medicine, University of Pennsylvania; School of Medicine, New York University; University of Illinois at Urbana-Champaign; National Center for Research Resources; National Institute of General Medical Sciences; Duke Global Health Institute, Duke University; Centers for Disease Control and Prevention; National Institutes of Health; Högskolan Dalarna; Universitair Medisch Centrum Groningen; Otsuka Pharmaceutical; Karolinska Institutet; British Heart Foundation; Bundesministerium für Bildung und Forschung; Rijksuniversiteit Groningen; Boehringer Ingelheim France; University of New South Wales; Institut National de la Santé et de la Recherche Médicale; Deutsche Forschungsgemeinschaft; University of Leicester; Academy of Medical Sciences; British Renal Society; University of California, San Francisco; GlaxoSmithKline; Shahid Beheshti University of Medical Sciences; Diabetes UK; Kidney Research UK; National Center for Advancing Translational Sciences; Kaiser Permanente; Universidad de la República Uruguay; National Institute for Health and Care Research; Albert-Ludwigs-Universität Freiburg; University Hospitals of Leicester NHS Trust; Deutsches Krebsforschungszentrum; Geisinger Commonwealth School of Medicine; Georgia Clinical and Translational Science Alliance; Tulane University; Michigan Institute for Clinical and Health Research; Sanofi; National Institute of Diabetes and Digestive and Kidney Diseases; MSD France; University of Pennsylvania; Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences; Eli Lilly and Company; Brigham and Women's Hospital; Wellcome Trust; University of Oxford; University of Dundee; Tufts Medical Center; York University; AstraZeneca; Duke-NUS Medical School; Johns Hopkins University; University of California, Los Angeles; University of Washington; Imperial College London; Università degli Studi di Salerno; Amgen","keywords":"Medicine; Albuminuria; Renal function; Creatinine; Kidney disease; Cystatin C; Internal medicine; Population; Urology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01132332,0.001124137,0.001770445,0.0016894,0.0002420876,0.001209518,0.0008875368,0.000842493,0.001421755],"category_scores_gemma":[0.02600662,0.0003991805,0.004691991,0.002652521,0.000555598,0.0005317422,0.0006459819,0.001097865,0.0001503058],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006918945,"about_ca_system_score_gemma":0.001381723,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006886403,"about_ca_topic_score_gemma":0.007884032,"domain_scores_codex":[0.9896697,0.006411946,0.0009430938,0.001088561,0.001677113,0.0002095536],"domain_scores_gemma":[0.9865633,0.008982555,0.002688418,0.000708001,0.0008634735,0.0001942457],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00410239,0.0001741635,0.5812951,0.01403972,0.3120101,0.0002624011,0.00009216955,0.01060602,0.0005400114,0.001126032,0.007362925,0.06838901],"study_design_scores_gemma":[0.002591981,0.001324951,0.64098,0.006546604,0.304005,0.001138639,0.0001470083,0.01471137,0.001558757,0.008067062,0.01872586,0.0002027189],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1642727,0.8082666,0.0104003,0.00538516,0.00116789,0.0001949486,0.007358578,0.0001899851,0.00276387],"genre_scores_gemma":[0.9055352,0.08440653,0.004830163,0.001155541,0.0007670271,0.0002494527,0.002383486,0.00002511193,0.0006474687],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01132332,"threshold_uncertainty_score":0.05988413,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06370402878490815,"score_gpt":0.3671628416813921,"score_spread":0.303458812896484,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}