{"id":"W4387326520","doi":"10.1111/jgs.18611","title":"Accelerated aging mediates the associations of unhealthy lifestyles with cardiovascular disease, cancer, and mortality","year":2023,"lang":"en","type":"article","venue":"Journal of the American Geriatrics Society","topic":"Genetics, Aging, and Longevity in Model Organisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":98,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health and Social Services Centre University Institute of Geriatrics of Sherbrooke; Centre Hospitalier Universitaire de Sherbrooke; Université de Sherbrooke","funders":"Key Research and Development Program of Zhejiang Province; Zhejiang University; National Institute on Aging; Fundamental Research Funds for the Central Universities; National Natural Science Foundation of China; Yale University","keywords":"Medicine; Disease; Gerontology; Cancer; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008213791,0.0001159768,0.0002734212,0.000021949,0.0002083979,0.00002991945,0.0003070176,0.00003708494,8.959883e-7],"category_scores_gemma":[0.0001265522,0.00006798397,0.0003595855,0.0004928451,0.0002916839,0.000005975084,0.0001316044,0.0001633615,1.734407e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000315962,"about_ca_system_score_gemma":0.0003463759,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003564499,"about_ca_topic_score_gemma":0.00003153573,"domain_scores_codex":[0.9988455,0.0001437904,0.0002788418,0.0001418612,0.0003992889,0.0001907172],"domain_scores_gemma":[0.9985543,0.00005444125,0.0006812266,0.0003392838,0.0002788468,0.00009189184],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00003986527,0.00006622278,0.9460637,0.000078611,0.002825371,0.000002761952,0.002320107,0.02802426,0.01268927,0.000009956139,0.005986145,0.001893708],"study_design_scores_gemma":[0.0003746384,0.0001128906,0.9928303,0.00001323963,0.0006663786,0.000005657585,0.0009177586,0.000436904,0.0028492,0.00008423161,0.001574689,0.0001341541],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927652,0.004793347,0.0004224799,0.001663301,0.0001802253,0.0001081979,0.00005763205,0.000005903592,0.000003686787],"genre_scores_gemma":[0.9812199,0.01764665,0.000323421,0.0003706254,0.0003846518,0.000004128772,0.000007528514,0.00001827521,0.00002479456],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04676654,"threshold_uncertainty_score":0.2772306,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02566276942292476,"score_gpt":0.2847936946882126,"score_spread":0.2591309252652879,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}