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Helmsley Charitable Trust; Croucher Foundation; Moonshot Research and Development Program; Canadian Institutes of Health Research; Diabetes UK; National Institute for Health and Care Research; John Templeton Foundation; British Heart Foundation; Boettcher Foundation; Diabetes Research Connection; Sun Pharma; Trond Mohn stiftelse; Bigfoot Biomedical; Dexcom; Insulet Corporation; Eli Lilly and Company; Immune Tolerance Network; MannKind Corporation; Doris Duke Charitable Foundation; Hong Kong Government; Wellcome Trust; Research England; AstraZeneca; European Commission; Steno Diabetes Center Copenhagen; Helsingin Yliopisto; KU Leuven; Hamilton Health Sciences; U.S. Department of Veterans Affairs; Daiichi Sankyo Europe; Yale University; Chinese University of Hong Kong; Sanofi; American Diabetes Association","keywords":"Precision medicine; Medicine; MEDLINE; Evidence-based medicine; Intensive care medicine; Common cause and special cause; Alternative medicine; Pathology; Political science; Engineering","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005721519,0.0003592108,0.002103427,0.0006645063,0.00007628928,0.000009340508,0.0002874862,0.0006811863,0.000318028],"category_scores_gemma":[0.004670265,0.0001695322,0.0003225598,0.0003001989,0.0007620591,0.00002414357,0.00007879677,0.001383923,0.000003610515],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003677192,"about_ca_system_score_gemma":0.0001714127,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001434361,"about_ca_topic_score_gemma":0.000005180365,"domain_scores_codex":[0.9963613,0.0001861531,0.001570411,0.000522401,0.001088139,0.0002715536],"domain_scores_gemma":[0.9901705,0.007999547,0.000705349,0.0005592594,0.0004054529,0.000159886],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001075217,0.00004468975,0.00003247365,0.01523423,0.001006024,0.00009758829,0.00003638666,4.770681e-8,0.000002033014,0.0003986402,0.1131116,0.8699288],"study_design_scores_gemma":[0.001950518,0.001182236,0.0001586295,0.03522844,0.002324813,0.00002477838,0.0001051899,0.00007542125,0.000001936661,0.000272912,0.9585485,0.000126621],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00007719645,0.954778,0.00001078563,0.0308196,0.00266499,0.002566189,0.00006386852,0.00004913629,0.008970258],"genre_scores_gemma":[0.0001042516,0.9771501,0.0000715987,0.000612093,0.002816193,0.0001226799,0.00101128,0.00006637826,0.01804536],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.8698021,"threshold_uncertainty_score":0.6913323,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3213265269663893,"score_gpt":0.5042445191692628,"score_spread":0.1829179922028735,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). 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