{"id":"W4387329458","doi":"10.1200/jco.23.00307","title":"Definitions, End Points, and Clinical Trial Designs for Bladder Cancer: Recommendations From the Society for Immunotherapy of Cancer and the International Bladder Cancer Group","year":2023,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Bladder and Urothelial Cancer Treatments","field":"Medicine","cited_by":53,"is_retracted":false,"has_abstract":true,"ca_institutions":"North York General Hospital; University of British Columbia","funders":"Society for Immunotherapy of Cancer","keywords":"Bladder cancer; Medicine; Clinical trial; Cancer; Cystectomy; Multidisciplinary approach; Immunotherapy; Disease; Clinical study design; Oncology; Family medicine; Internal medicine; Medical physics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.3959525,0.004501206,0.007367572,0.01207435,0.003567587,0.008473408,0.01275981,0.02010633,0.004603096],"category_scores_gemma":[0.4786711,0.003344026,0.01352904,0.007870385,0.007580548,0.00779934,0.007246116,0.04024968,0.00411094],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.009111721,"about_ca_system_score_gemma":0.06239922,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.007713116,"about_ca_topic_score_gemma":0.009576362,"domain_scores_codex":[0.6026298,0.2906186,0.06424101,0.005237421,0.03391681,0.003356354],"domain_scores_gemma":[0.4103925,0.3831902,0.03891902,0.01777604,0.1390762,0.01064596],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.002598923,0.0008680482,0.004032387,0.04061643,0.001511665,0.0003049192,0.002385299,0.004073097,0.001224066,0.03748911,0.4917505,0.4131456],"study_design_scores_gemma":[0.006775731,0.001409104,0.007448298,0.2245196,0.005504174,0.0008560545,0.001625024,0.004467221,0.002146762,0.09747675,0.6471981,0.000573203],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"methods","genre_scores_codex":[0.00248431,0.1911878,0.1018665,0.6347227,0.03109497,0.01831344,0.00398126,0.001116882,0.01523223],"genre_scores_gemma":[0.01356211,0.1194745,0.6259906,0.1745499,0.009273641,0.04690056,0.004609845,0.0006372954,0.005001538],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.3959525,"threshold_uncertainty_score":0.7448982,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3129307591216636,"score_gpt":0.5244787903783332,"score_spread":0.2115480312566696,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}