{"id":"W4387330788","doi":"10.1371/journal.pgen.1010990","title":"Functional dissection and assembly of a small, newly evolved, W chromosome-specific genomic region of the African clawed frog Xenopus laevis","year":2023,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; Max-Planck-Institut für Evolutionäre Anthropologie; Natural Sciences and Engineering Research Council of Canada; McMaster University; Museum of Comparative Zoology, Harvard University; Compute Canada; Foundation for the National Institutes of Health; Marine Biological Laboratory; National Institutes of Health; National Science Foundation","keywords":"Biology; Xenopus; Genetics; African clawed frog; Ciona intestinalis; Gene; Y chromosome; Evolutionary biology; Sexual differentiation; Transcriptome; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000750394,0.000206108,0.000146899,0.0002434535,0.0001873131,0.0002522271,0.0002464586,0.0002904517,0.0007992534],"category_scores_gemma":[0.0001307922,0.000202711,0.0002888002,0.0001342919,0.0002756173,0.0002044272,0.0002592648,0.0004479209,0.0004040535],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000198024,"about_ca_system_score_gemma":0.0001866649,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007543726,"about_ca_topic_score_gemma":0.00153591,"domain_scores_codex":[0.9999319,0.000006408213,0.000006147064,0.00002776127,0.00001649246,0.00001125836],"domain_scores_gemma":[0.9998548,0.00002255876,0.00006474012,0.00001974488,0.000008428196,0.00002970558],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00001687012,0.000003057511,0.0003322361,0.00001219311,0.000001994937,0.00005211654,0.00001030363,0.00003529483,0.9989734,0.00007309669,0.000005101435,0.0004843213],"study_design_scores_gemma":[0.00001560321,0.0001965194,0.07095382,0.0000151652,0.00003053307,0.001506017,0.0001141053,0.001303541,0.9199892,0.0001340689,0.005730782,0.00001068391],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9906057,0.0006116937,0.007207945,0.0000474784,0.000009344129,0.00002216767,0.0004922212,0.00007862684,0.0009249159],"genre_scores_gemma":[0.9884661,0.0003984916,0.007276577,0.00005804732,0.000007139101,0.00002713661,0.001207027,0.00007696521,0.002482392],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007992534,"threshold_uncertainty_score":0.002673745,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03142872232346724,"score_gpt":0.2319871110340328,"score_spread":0.2005583887105655,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}