{"id":"W4387330788","doi":"10.1371/journal.pgen.1010990","title":"Functional dissection and assembly of a small, newly evolved, W chromosome-specific genomic region of the African clawed frog Xenopus laevis","year":2023,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; Max-Planck-Institut für Evolutionäre Anthropologie; Natural Sciences and Engineering Research Council of Canada; McMaster University; Museum of Comparative Zoology, Harvard University; Compute Canada; Foundation for the National Institutes of Health; Marine Biological Laboratory; National Institutes of Health; National Science Foundation","keywords":"Biology; Xenopus; Genetics; African clawed frog; Ciona intestinalis; Gene; Y chromosome; Evolutionary biology; Sexual differentiation; Transcriptome; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008769465,0.0001458107,0.0001921346,0.00008556147,0.00009182306,0.00001558575,0.0001910245,0.0001432962,0.00002319602],"category_scores_gemma":[0.0000409475,0.0001174187,0.0001183166,0.0003129655,0.000219924,0.000003132233,0.0001736376,0.00008269032,0.000005661872],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008562365,"about_ca_system_score_gemma":0.00005006088,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006419205,"about_ca_topic_score_gemma":0.0000276192,"domain_scores_codex":[0.9989253,0.00006390866,0.000365353,0.0002761036,0.0001887488,0.0001805904],"domain_scores_gemma":[0.9992334,0.00003720793,0.0001923782,0.0003249105,0.0001445145,0.00006761726],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009045154,0.0001117191,0.004351318,0.00007442197,0.00007483447,0.000001865646,0.0001374725,0.0001665193,0.9920788,0.0001426111,0.00104251,0.0017275],"study_design_scores_gemma":[0.0006331761,0.0005649657,0.0448777,0.00004041412,0.00006429503,0.00002489104,0.0007251793,0.0005437717,0.9438688,0.0002897165,0.008163013,0.0002041375],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977147,0.0009511187,0.0000601827,0.0002757032,0.0001799883,0.0001830258,0.00002551717,0.00001465456,0.0005951312],"genre_scores_gemma":[0.996163,0.0021099,0.0001806027,0.00005794317,0.0002053078,0.00001617913,0.00004853293,0.00002055459,0.001197984],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04821004,"threshold_uncertainty_score":0.4788198,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03142872232346724,"score_gpt":0.2319871110340328,"score_spread":0.2005583887105655,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}