{"id":"W4387333897","doi":"10.7554/elife.90893.1","title":"Increasing adult neurogenesis protects mice from epilepsy","year":2023,"lang":"en","type":"preprint","venue":"","topic":"Neurogenesis and neuroplasticity mechanisms","field":"Neuroscience","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"National Institutes of Health; New York State Office of Mental Health","keywords":"Neurogenesis; Epileptogenesis; Dentate gyrus; Epilepsy; Hippocampal formation; Status epilepticus; Nestin; Neuroscience; Endocrinology; Internal medicine; Psychology; Medicine; Biology; Stem cell; Neural stem cell; Cell biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002181337,0.0007531045,0.0005499625,0.001114594,0.0002315387,0.0003494321,0.0003637574,0.000669112,0.005039498],"category_scores_gemma":[0.0001271987,0.0003410789,0.0003798865,0.0002883886,0.0004270363,0.0002074649,0.0004330133,0.0009735669,0.001517093],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002765581,"about_ca_system_score_gemma":0.0002522572,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004951306,"about_ca_topic_score_gemma":0.0009094684,"domain_scores_codex":[0.9997773,0.00002279359,0.00002475821,0.0000541617,0.00006375724,0.00005725075],"domain_scores_gemma":[0.9996058,0.00003638854,0.0001453409,0.00004329343,0.00002968414,0.0001394794],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005168137,0.0001313096,0.0002669327,0.00005117224,0.00001188044,0.0001132435,0.00002451586,0.00009050575,0.9953015,0.0003198378,0.0002411294,0.002931128],"study_design_scores_gemma":[0.0002047071,0.001300672,0.006154419,0.00003633208,0.00004037862,0.0004499883,0.00006062653,0.0008209684,0.9835068,0.0003358853,0.007074218,0.00001507411],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9850137,0.00153624,0.004445311,0.0005214101,0.0001434742,0.0000549936,0.002287919,0.0009579916,0.005039002],"genre_scores_gemma":[0.9571666,0.001722306,0.007156171,0.0003425137,0.00007270039,0.0002124478,0.002830083,0.0006183734,0.02987887],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005039498,"threshold_uncertainty_score":0.01685876,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07465520922702852,"score_gpt":0.2733114444195983,"score_spread":0.1986562351925698,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}