{"id":"W4387337873","doi":"10.1016/j.cjca.2023.06.347","title":"RENAL TUBULE-SPECIFIC ANGIOTENSINOGEN KNOCKOUT AMELIORATES DIABETIC KIDNEY DISEASE IN TYPE 1 DIABETIC AKITA MICE","year":2023,"lang":"en","type":"article","venue":"Canadian Journal of Cardiology","topic":"Diabetes Treatment and Management","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"","keywords":"Medicine; Renin–angiotensin system; Internal medicine; Endocrinology; Kidney; Diabetes mellitus; Disease; Proximal tubule; Kidney disease; Knockout mouse; Type 2 diabetes; Receptor; Blood pressure","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005334536,0.00103288,0.001145697,0.001395465,0.0006964689,0.001034411,0.0007376292,0.001410269,0.005514902],"category_scores_gemma":[0.0003884844,0.0006883866,0.001020934,0.0005384099,0.0007049886,0.0007622608,0.0004901563,0.003349799,0.0008393735],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005794551,"about_ca_system_score_gemma":0.0007429318,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001824105,"about_ca_topic_score_gemma":0.003515542,"domain_scores_codex":[0.9992913,0.0000816027,0.00009878392,0.0001732426,0.0001821698,0.0001729696],"domain_scores_gemma":[0.998939,0.00007319566,0.0003864484,0.00006514144,0.00008309467,0.0004531213],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002392616,0.0008069625,0.0008100267,0.0001836808,0.00007784546,0.00047806,0.00008924465,0.0002613892,0.9904029,0.0007474309,0.0004523997,0.00329743],"study_design_scores_gemma":[0.001440917,0.003243474,0.03401577,0.0001989095,0.0008052776,0.002601871,0.0006537574,0.006529689,0.9367136,0.001439162,0.01223613,0.0001214141],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9838307,0.001544821,0.007335565,0.0009103662,0.0005214772,0.0001088282,0.00220126,0.0007479226,0.002799198],"genre_scores_gemma":[0.9797243,0.002042332,0.00562539,0.0005158912,0.0001501644,0.0002008757,0.001370501,0.0002862572,0.01008436],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005514902,"threshold_uncertainty_score":0.01844913,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01994864025275747,"score_gpt":0.2366999434858278,"score_spread":0.2167513032330703,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}