{"id":"W4387338029","doi":"10.1016/j.cjca.2023.06.170","title":"CELLULAR COMMUNICATION NETWORK FACTOR 5 (CCN5) GENE DEFICIENCY CAUSES IMPROVED INSULIN SENSITIVITY AND GLUCOSE TOLERANCE IN DIET-INDUCED OBESITY IN MALE MICE","year":2023,"lang":"en","type":"article","venue":"Canadian Journal of Cardiology","topic":"Connective Tissue Growth Factor Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"","keywords":"Medicine; Diabetes mellitus; Matricellular protein; Metabolic syndrome; Wnt signaling pathway; Growth factor; Insulin resistance; Insulin sensitivity; Endocrinology; Obesity; Internal medicine; Signal transduction; Cell biology; Receptor; Biology; Extracellular matrix","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002587427,0.001006137,0.0003696051,0.001443304,0.0004536904,0.0004711898,0.0006285006,0.0008564435,0.005004181],"category_scores_gemma":[0.0002628083,0.0004555382,0.0005100814,0.0004324705,0.0008383751,0.0003172873,0.0004327559,0.001240419,0.0005455342],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006684389,"about_ca_system_score_gemma":0.000460695,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002535548,"about_ca_topic_score_gemma":0.004600757,"domain_scores_codex":[0.9995382,0.00006873321,0.00005045962,0.0001174802,0.0001387226,0.00008652492],"domain_scores_gemma":[0.9993604,0.00005727612,0.0002824973,0.00004003631,0.00002655739,0.0002332759],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008219111,0.0001127515,0.0005212583,0.00005054174,0.00002528238,0.000345214,0.00002819284,0.0001337585,0.9961743,0.0004125364,0.0001193643,0.001254772],"study_design_scores_gemma":[0.0003240009,0.0007604344,0.02341371,0.0000593101,0.0002492043,0.001577016,0.0001904639,0.002989854,0.9659979,0.0003526871,0.004046548,0.00003872359],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.992146,0.001095902,0.003648802,0.0003139842,0.0001394719,0.00002777667,0.001100091,0.0002083137,0.001319709],"genre_scores_gemma":[0.9867611,0.000891684,0.003160728,0.000176202,0.000044196,0.00008068069,0.0007897517,0.0001737679,0.007921878],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005004181,"threshold_uncertainty_score":0.01674062,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02177890985240121,"score_gpt":0.2561036909903849,"score_spread":0.2343247811379837,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}