{"id":"W4387338234","doi":"10.1016/j.cjca.2023.06.102","title":"PENTRAXIN-3 AS A NOVEL CARDIOTOXIC BIOMARKER FOR BREAST CANCER PATIENTS RECEIVING ANTHRACYCLINES AND THE IMPACT OF PHYSICAL ACTIVITY: AN INTERIM REPORT FROM THE EXACT 2.0 TRIAL","year":2023,"lang":"en","type":"article","venue":"Canadian Journal of Cardiology","topic":"Chemotherapy-induced cardiotoxicity and mitigation","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"","keywords":"Medicine; Cardiotoxicity; Breast cancer; Anthracycline; Interim; Biomarker; Interim analysis; Oncology; Cancer; Internal medicine; Clinical trial; Intensive care medicine; Bioinformatics; Chemotherapy","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001253737,0.0006571205,0.001381573,0.000111143,0.0002255565,0.001287721,0.0003556561,0.0009105453,0.001771796],"category_scores_gemma":[0.001305985,0.0002738498,0.001292233,0.0002079557,0.0004172241,0.0004948435,0.0003811195,0.002420811,0.0003206872],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006331665,"about_ca_system_score_gemma":0.0007901287,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008494391,"about_ca_topic_score_gemma":0.003091168,"domain_scores_codex":[0.9996161,0.0001898194,0.00001891894,0.00005812996,0.0000461924,0.00007070696],"domain_scores_gemma":[0.9994155,0.0001464584,0.0001824545,0.0000605373,0.00006281755,0.000132273],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.7906928,0.006053104,0.02977472,0.0008984848,0.006670089,0.0001511083,0.0001784442,0.001763994,0.01879866,0.0007847957,0.004666856,0.1395669],"study_design_scores_gemma":[0.5238461,0.2489807,0.1783231,0.0004364566,0.01418401,0.0005799904,0.0003009826,0.003916913,0.008236376,0.002975944,0.01804769,0.0001717265],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9878461,0.00680789,0.0004388611,0.001368205,0.000282457,0.0004185646,0.00078424,0.00005029138,0.00200343],"genre_scores_gemma":[0.9909422,0.003068719,0.001152664,0.001383897,0.0002337085,0.0003807933,0.001174737,0.00001771942,0.001645614],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001771796,"threshold_uncertainty_score":0.00663048,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04369169298066103,"score_gpt":0.3577772025103675,"score_spread":0.3140855095297065,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}