{"id":"W4387343815","doi":"10.1136/ard-2023-224803","title":"Bimekizumab treatment in patients with active axial spondyloarthritis: 52-week efficacy and safety from the randomised parallel phase 3 BE MOBILE 1 and BE MOBILE 2 studies","year":2023,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Spondyloarthritis Studies and Treatments","field":"Medicine","cited_by":50,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"UCB Pharma","keywords":"Medicine; Ankylosing spondylitis; Axial spondyloarthritis; Placebo; Internal medicine; Clinical endpoint; Adverse effect; Spondylitis; Gastroenterology; Randomized controlled trial; Pathology; Sacroiliitis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005196122,0.001601432,0.003687665,0.0004832816,0.0006724416,0.001381454,0.0009932455,0.002300634,0.006760245],"category_scores_gemma":[0.002802073,0.00102477,0.002754984,0.0005137652,0.0009375177,0.001322648,0.0007380036,0.002746551,0.001323063],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008573144,"about_ca_system_score_gemma":0.001290637,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005528993,"about_ca_topic_score_gemma":0.001463425,"domain_scores_codex":[0.9981639,0.001047439,0.0001475491,0.0002320145,0.0001643648,0.0002448186],"domain_scores_gemma":[0.998019,0.000409861,0.0006270986,0.0002682203,0.0001887671,0.0004870614],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9684627,0.008567871,0.00120535,0.0005739116,0.0007567618,0.00003771174,0.0000752327,0.0001924538,0.003647778,0.00004682982,0.0006987549,0.01573461],"study_design_scores_gemma":[0.8664517,0.123642,0.007274487,0.00005697489,0.0005397856,0.00007123248,0.00002643476,0.0001767758,0.0005291234,0.00007955277,0.001126859,0.00002506997],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9848078,0.006136472,0.0006450951,0.0004795435,0.0002713111,0.004408772,0.001465117,0.00009581646,0.001690112],"genre_scores_gemma":[0.9832607,0.002824961,0.001479848,0.001084014,0.0004194398,0.006408732,0.002144636,0.00003635429,0.002341331],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006760245,"threshold_uncertainty_score":0.02748007,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03977633189661097,"score_gpt":0.325611915263223,"score_spread":0.285835583366612,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}