{"id":"W4387357326","doi":"10.3324/haematol.2023.283303","title":"Brentuximab vedotin with chemotherapy in adolescents and young adults with stage III or IV classical Hodgkin lymphoma in ECHELON-1","year":2023,"lang":"en","type":"letter","venue":"Haematologica","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"National Cancer Institute; Seagen","keywords":"Brentuximab vedotin; Classical Hodgkin lymphoma; Chemotherapy; Medicine; Stage (stratigraphy); Hodgkin lymphoma; Oncology; Internal medicine; Lymphoma; Pediatrics; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001389231,0.0007556083,0.001752146,0.000391944,0.00006020245,0.00006186725,0.0001956908,0.0009016633,0.00007013787],"category_scores_gemma":[0.00004190352,0.0004205865,0.00009731798,0.0005619765,0.0002513666,0.00006555157,0.000092596,0.0006952087,0.00006355918],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004521488,"about_ca_system_score_gemma":0.000325618,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007733335,"about_ca_topic_score_gemma":0.002459817,"domain_scores_codex":[0.9966702,0.0001363069,0.0005930357,0.001151276,0.0006176053,0.0008315532],"domain_scores_gemma":[0.9987885,0.0001464651,0.0002794852,0.0005749254,0.00006016544,0.00015044],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01285773,0.002876223,0.7269962,0.00241222,0.0003346361,0.1510751,0.0009459682,9.023137e-7,0.000003965162,0.00002169554,0.09169456,0.01078089],"study_design_scores_gemma":[0.07762616,0.00412899,0.8600975,0.01731816,0.0002512322,0.004582033,0.0005570735,0.0001617373,0.0002286599,0.00002043786,0.0338748,0.001153161],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8889869,0.0004357475,0.000005098336,0.1076416,0.0001175375,0.002125992,0.00005141775,0.0001996688,0.0004360361],"genre_scores_gemma":[0.9292951,0.0009048029,0.0004432788,0.06609961,0.000230962,0.0007079488,0.0002892789,0.0001563147,0.00187274],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.146493,"threshold_uncertainty_score":0.9998246,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01932127148719474,"score_gpt":0.2560877336693754,"score_spread":0.2367664621821807,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}