{"id":"W4387366247","doi":"10.3389/fnagi.2023.1258315","title":"Neuroimaging and serum biomarkers of neurodegeneration and neuroplasticity in Parkinson’s disease patients treated by intermittent theta-burst stimulation over the bilateral primary motor area: a randomized, double-blind, sham-controlled, crossover trial study","year":2023,"lang":"en","type":"article","venue":"Frontiers in Aging Neuroscience","topic":"Transcranial Magnetic Stimulation Studies","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Sociedad Andaluza de Neurología; Ministerio de Ciencia e Innovación; Ministry of Health, British Columbia; European Regional Development Fund; Ministerio de Ciencia, Innovación y Universidades","keywords":"Transcranial magnetic stimulation; Primary motor cortex; Neuroscience; Neuroplasticity; Medicine; Brain stimulation; Parkinson's disease; Stimulation; Motor cortex; Transcranial direct-current stimulation; Psychology; Functional magnetic resonance imaging; Neurocognitive; Physical medicine and rehabilitation; Disease; Internal medicine","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001439752,0.001878176,0.004508789,0.0004553413,0.0006151608,0.0008170732,0.0007004724,0.00222163,0.003529375],"category_scores_gemma":[0.001153231,0.0007108059,0.001556028,0.0004728709,0.001034938,0.0008269437,0.0003391852,0.001476787,0.000520032],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005354043,"about_ca_system_score_gemma":0.0009523391,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005606937,"about_ca_topic_score_gemma":0.0008408717,"domain_scores_codex":[0.9993256,0.0002535231,0.00006616776,0.0001667158,0.00007627914,0.000111752],"domain_scores_gemma":[0.9989458,0.0001737354,0.0003114938,0.00008360126,0.0001106586,0.0003747538],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9691288,0.01662367,0.002526541,0.0003088968,0.0006421109,0.00003387367,0.00004070695,0.0001130204,0.003238909,0.00002314557,0.0001466807,0.007173785],"study_design_scores_gemma":[0.7295491,0.2554653,0.01269795,0.00002271233,0.0007875662,0.00004839452,0.00002663294,0.0003121025,0.0007559319,0.00006049107,0.000253543,0.00002029951],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962577,0.001248871,0.0001933398,0.00008189419,0.00008799583,0.001591632,0.0001767932,0.00002063649,0.0003411289],"genre_scores_gemma":[0.9938524,0.0007330696,0.0006382988,0.0001983091,0.0001902745,0.003465197,0.0003563997,0.000004208196,0.0005618128],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004508789,"threshold_uncertainty_score":0.01180691,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03183903244404973,"score_gpt":0.2745210363927822,"score_spread":0.2426820039487325,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}