{"id":"W4387396656","doi":"10.1016/j.fertnstert.2023.08.269","title":"IN-VITRO TREATMENT OF HUMAN OOCYTES WITH CANNABIS ALTERS GENES INVOLVED IN CHROMOSOMAL ORGANIZATION AND SEGREGATION - A SINGLE CELL RNASEQ STUDY","year":2023,"lang":"en","type":"article","venue":"Fertility and Sterility","topic":"Reproductive Biology and Fertility","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"CReATe Fertility Centre","funders":"","keywords":"Oocyte; Transcriptome; Andrology; Biology; Cannabis; Follicular phase; Follicular fluid; Cannabinol; Gene; Gene expression; Endocrinology; Cannabinoid; Genetics; Embryo; Medicine; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001688975,0.0001583202,0.0002936647,0.0001912162,0.0002933879,0.0002152992,0.0002571153,0.0002934663,0.002862103],"category_scores_gemma":[0.0002099377,0.0001490962,0.0004155027,0.0001410506,0.0002819107,0.0001632728,0.0001512118,0.0004309866,0.0004332404],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002667344,"about_ca_system_score_gemma":0.0002716082,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003269979,"about_ca_topic_score_gemma":0.003387149,"domain_scores_codex":[0.9998888,0.00001979014,0.000007350029,0.00002704852,0.00002783292,0.00002906075],"domain_scores_gemma":[0.9998732,0.00005380542,0.00001498159,0.00002151139,0.00002151631,0.00001491486],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000108154,0.00001336582,0.0001312723,0.000009149867,0.000003603718,0.0000304897,0.00001639418,0.00001409199,0.9993357,0.00003272968,0.00001279945,0.0002921945],"study_design_scores_gemma":[0.00001762585,0.0003628801,0.005203717,0.000002130475,0.000024427,0.0002405327,0.00007689733,0.000279496,0.9925438,0.00004793127,0.001196383,0.000004203557],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944025,0.001202477,0.00219346,0.0001095005,0.00003500231,0.00003954305,0.0004156938,0.00002188267,0.001580005],"genre_scores_gemma":[0.9941546,0.0005128753,0.0008757925,0.00003808845,0.00001002481,0.00002051894,0.0005211519,0.00002055214,0.003846328],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003269979,"threshold_uncertainty_score":0.009574652,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0322379151322271,"score_gpt":0.2727850342015182,"score_spread":0.2405471190692911,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}