{"id":"W4387405937","doi":"10.1210/jendso/bvad114.331","title":"SAT327 A Curious Case of Immune Checkpoint Inhibitor Induced Hypophysitis with Transient ACTH-dependent Hypercortisolism","year":2023,"lang":"en","type":"article","venue":"Journal of the Endocrine Society","topic":"Neuroendocrine Tumor Research Advances","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Jewish General Hospital; McGill University","funders":"","keywords":"Hypophysitis; Medicine; Levothyroxine; Nivolumab; Internal medicine; Endocrinology; Hypokalemia; Hypopituitarism; Adrenal insufficiency; Ipilimumab; Thyroid; Gastroenterology; Pituitary gland; Hormone; Immunotherapy; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000280059,0.001256775,0.0007777495,0.001719234,0.001499751,0.001044229,0.001029927,0.003510554,0.002199227],"category_scores_gemma":[0.001847846,0.0008825164,0.001238152,0.001052067,0.001097374,0.001130211,0.001055192,0.003321915,0.0007037146],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001449813,"about_ca_system_score_gemma":0.0007081621,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002347317,"about_ca_topic_score_gemma":0.002517265,"domain_scores_codex":[0.9995539,0.00005109331,0.00004915358,0.0001240789,0.00007920441,0.0001424494],"domain_scores_gemma":[0.9990652,0.000227145,0.0001407342,0.000131528,0.00007452591,0.0003608516],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.00005539782,0.0000236752,0.002954115,0.00003189644,0.00001212158,0.9938116,0.00008620544,0.00006451755,0.001593157,0.0001743179,0.0002392153,0.0009536842],"study_design_scores_gemma":[0.00001865395,0.00008476918,0.003931865,0.00001424282,0.00001124456,0.9941923,0.00006036846,0.0003369559,0.0005601094,0.0001931678,0.0005877272,0.000008615999],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9652268,0.005463585,0.003899363,0.005736775,0.0007683428,0.000200366,0.0004454433,0.0003169992,0.0179422],"genre_scores_gemma":[0.9969446,0.0004499363,0.0006535213,0.0007318745,0.0003102052,0.00001393659,0.00008063837,0.00001437843,0.0008009573],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003510554,"threshold_uncertainty_score":0.01051915,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02023915432476239,"score_gpt":0.3053726557511909,"score_spread":0.2851335014264285,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}