{"id":"W4387417605","doi":"10.5267/j.ccl.2023.8.007","title":"New biocidal hybrids bearing acridine and aminophosphonate Scaffolds against different bacterial pathogens","year":2023,"lang":"en","type":"article","venue":"Current Chemistry Letters","topic":"Synthesis and biological activity","field":"Chemistry","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Chemistry; Serratia marcescens; Acridine; Minimum inhibitory concentration; Antibacterial activity; Bacteria; Nuclear chemistry; Tetracycline; Antimicrobial; Chloramphenicol; Microbiology; Combinatorial chemistry; Antibiotics; Escherichia coli; Organic chemistry; Biochemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00009675919,0.0003693674,0.0003534418,0.000022571,0.0001379257,0.0001013102,0.0002718202,0.0001409073,0.000767616],"category_scores_gemma":[0.00007764931,0.000301405,0.0001704259,0.0001282061,0.0001082899,0.00006358446,0.0003305121,0.0002135236,0.00003601012],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009386289,"about_ca_system_score_gemma":0.00002120497,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001247276,"about_ca_topic_score_gemma":5.879161e-7,"domain_scores_codex":[0.9982283,0.00001374349,0.0002790892,0.0006385436,0.0002436364,0.0005966566],"domain_scores_gemma":[0.9991303,0.0001109867,0.0001144642,0.000318786,0.00001695917,0.0003085208],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003684879,0.0000515926,0.008008034,0.0001816442,0.00003444648,0.00002325502,0.00002728528,0.000001369515,0.9223309,8.580405e-7,0.001922981,0.06738076],"study_design_scores_gemma":[0.0005270206,0.000002392362,0.01051833,0.0001120205,0.00003005226,0.000007906282,0.00002721894,0.00008490546,0.9827173,0.00001425545,0.005543101,0.0004154485],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977365,0.0001834839,0.00001466384,0.0009290594,0.0004201299,0.00004895724,0.0001307656,0.0002881793,0.0002482746],"genre_scores_gemma":[0.9979975,0.000313092,0.00003260163,0.0000407135,0.001096855,0.00001848296,0.0003448293,0.00002901082,0.0001269153],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06696531,"threshold_uncertainty_score":0.9999438,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01968162738862654,"score_gpt":0.2279089754353522,"score_spread":0.2082273480467257,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}