{"id":"W4387417605","doi":"10.5267/j.ccl.2023.8.007","title":"New biocidal hybrids bearing acridine and aminophosphonate Scaffolds against different bacterial pathogens","year":2023,"lang":"en","type":"article","venue":"Current Chemistry Letters","topic":"Synthesis and biological activity","field":"Chemistry","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Chemistry; Serratia marcescens; Acridine; Minimum inhibitory concentration; Antibacterial activity; Bacteria; Nuclear chemistry; Tetracycline; Antimicrobial; Chloramphenicol; Microbiology; Combinatorial chemistry; Antibiotics; Escherichia coli; Organic chemistry; Biochemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009758187,0.0006577884,0.000278733,0.0003266674,0.0001347771,0.0002314468,0.0003490238,0.0004605569,0.001426471],"category_scores_gemma":[0.0001125793,0.0002652518,0.0002639664,0.0002526259,0.0001756169,0.0003682962,0.000315854,0.0004208592,0.0005499238],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001860382,"about_ca_system_score_gemma":0.000107699,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001970285,"about_ca_topic_score_gemma":0.0004132412,"domain_scores_codex":[0.999904,0.00001326066,0.000008490821,0.00002431505,0.00002162918,0.00002831111],"domain_scores_gemma":[0.9999232,0.000009675106,0.00002998776,0.000006855655,0.00001180775,0.00001841182],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009175789,0.00002692639,0.00005245067,0.0001860086,0.000009818069,0.0001509714,0.00002591092,0.000349678,0.9939229,0.0003694579,0.00009020042,0.004723853],"study_design_scores_gemma":[0.00002269476,0.0007832355,0.001046625,0.0000118812,0.00003165517,0.0003642387,0.00001755774,0.0007538554,0.9903066,0.00007684161,0.006564036,0.0000209036],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9619889,0.00677109,0.01861191,0.0002051622,0.0001471885,0.0001242358,0.000662201,0.0005514988,0.01093772],"genre_scores_gemma":[0.9838145,0.002012352,0.01046948,0.00008754199,0.00002666666,0.00008936084,0.0003064197,0.00002697624,0.003166616],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001426471,"threshold_uncertainty_score":0.004772007,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01968162738862654,"score_gpt":0.2279089754353522,"score_spread":0.2082273480467257,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}