{"id":"W4387417611","doi":"10.5267/j.ccl.2023.8.003","title":"Multicomponent approach to the synthesis and spectral characterization of some 3,5-pyrazolididione derivatives and evaluation as anti-inflammatory agents","year":2023,"lang":"en","type":"article","venue":"Current Chemistry Letters","topic":"Synthesis and biological activity","field":"Chemistry","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Chemistry; Diethyl malonate; Phenylhydrazine; Pyrazolones; Yield (engineering); Pyrazolone; Imidazole; Pyrazole; Malononitrile; Catalysis; Organic chemistry","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002198125,0.0004446151,0.0003342477,0.0006182463,0.0002218953,0.0002291597,0.0003917633,0.0004004998,0.001847207],"category_scores_gemma":[0.0002298457,0.0002292307,0.0003208502,0.0007428384,0.0001863151,0.0003340091,0.0003135462,0.000606699,0.0006303612],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002334793,"about_ca_system_score_gemma":0.0002709006,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005239148,"about_ca_topic_score_gemma":0.00171725,"domain_scores_codex":[0.9997904,0.00001983117,0.00001641904,0.00005286462,0.0000820229,0.00003853811],"domain_scores_gemma":[0.9998605,0.00001930448,0.00003325078,0.00001987135,0.00004534081,0.00002171092],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007500635,0.00008349182,0.0000962883,0.0001595285,0.00001118685,0.0001217844,0.00004311987,0.0002687346,0.9927239,0.0001848819,0.0001036408,0.00612833],"study_design_scores_gemma":[0.00001947174,0.0005640798,0.001235129,0.00001086621,0.00002853456,0.0001804093,0.00003224453,0.001104969,0.9929696,0.00008813982,0.003747727,0.00001890407],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9333151,0.009535263,0.04525817,0.0002883618,0.0001399067,0.0004294108,0.001030302,0.0004025675,0.009601099],"genre_scores_gemma":[0.947939,0.004210786,0.0391649,0.0001601204,0.00002570627,0.0003065834,0.0005870282,0.00005469078,0.007551194],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001847207,"threshold_uncertainty_score":0.006179512,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04432316017263485,"score_gpt":0.2715619159715176,"score_spread":0.2272387557988827,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}