{"id":"W4387431855","doi":"10.1093/femspd/ftad026","title":"TargeTron inactivation of plasmid-regulated <i>Chlamydia trachomatis</i> CT084 results in a nonlytic phenotype","year":2023,"lang":"en","type":"article","venue":"Pathogens and Disease","topic":"Reproductive tract infections research","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health; National Natural Science Foundation of China","keywords":"Lytic cycle; Chlamydiae; Chlamydia trachomatis; Biology; Microbiology; Virulence; Plasmid; Phenotype; Gene; Chlamydia; Virology; Genetics; Virus","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001176656,0.0005172263,0.0002826839,0.0002864999,0.0001720762,0.0002442177,0.0004562515,0.000548605,0.002690744],"category_scores_gemma":[0.0001781238,0.0001842713,0.0004240124,0.0002130315,0.000342789,0.0001743419,0.000367967,0.0009541866,0.0006678897],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004176302,"about_ca_system_score_gemma":0.0003212812,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00166679,"about_ca_topic_score_gemma":0.001654493,"domain_scores_codex":[0.9996847,0.00004276868,0.00003419618,0.00005591477,0.0001123555,0.00007011177],"domain_scores_gemma":[0.9996978,0.00006576905,0.0001001465,0.00004716782,0.00002314052,0.00006603717],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005402248,0.00002445093,0.00007479636,0.00001514779,0.000002189125,0.0000395754,0.000006878506,0.00002456067,0.9993505,0.00005383764,0.00003190067,0.0003223181],"study_design_scores_gemma":[0.00001383506,0.0002339966,0.003560443,0.000006404835,0.000008025529,0.0003280205,0.00002510463,0.0007150188,0.9936674,0.00002448219,0.001409986,0.000007133004],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940826,0.0003821585,0.002609348,0.0001112514,0.0000556976,0.00004010317,0.001086171,0.0002349702,0.001397688],"genre_scores_gemma":[0.9875582,0.0002282311,0.003305157,0.00008163777,0.00000801121,0.00006992284,0.001771222,0.0001357156,0.006841897],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002690744,"threshold_uncertainty_score":0.009001374,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01582149754048499,"score_gpt":0.2640026286786289,"score_spread":0.2481811311381439,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}