{"id":"W4387453245","doi":"10.1101/2023.10.06.561232","title":"N-cadherin mechanosensing in ovarian follicles controls oocyte maturation and ovulation","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Reproductive Biology and Fertility","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Merck Canada Inc. (Canada)","funders":"National Health and Medical Research Council; Cancer Council South Australia; Government of South Australia; University of Adelaide; Bill and Melinda Gates Foundation","keywords":"Adherens junction; Oocyte; Ovulation; Folliculogenesis; Cadherin; Ovarian follicle; Cell biology; Biology; Follicular phase; Granulosa cell; Catenin; Internal medicine; Endocrinology; Wnt signaling pathway; Signal transduction; Cell; Hormone; Medicine; Genetics; Embryogenesis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005622307,0.0001020061,0.0001694875,0.0001243034,0.0001416154,0.0002052144,0.00009962633,0.0001913187,0.001051201],"category_scores_gemma":[0.00007657128,0.00009607941,0.0001138934,0.00005446864,0.0001352213,0.0001526117,0.0001722666,0.0002174922,0.0001506958],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002626089,"about_ca_system_score_gemma":0.0001367716,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005983684,"about_ca_topic_score_gemma":0.00103923,"domain_scores_codex":[0.9999363,0.00000619587,0.000003252216,0.00001277935,0.00001797484,0.00002349106],"domain_scores_gemma":[0.9999498,0.00000422732,0.00001571275,0.000003223606,0.00000817774,0.00001875044],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006752153,0.000007492253,0.0004440504,0.00002119131,0.000001772659,0.00002555372,0.000007540711,0.00002837377,0.9983768,0.00007227992,0.00003924474,0.0009081553],"study_design_scores_gemma":[0.00004894032,0.000431044,0.1590683,0.00001938471,0.00002933283,0.0003253954,0.0001582805,0.002755545,0.828919,0.0002935652,0.007938182,0.00001300737],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938388,0.002531721,0.001237414,0.0001032842,0.00002653844,0.0000162587,0.0002118736,0.00005975359,0.001974296],"genre_scores_gemma":[0.9968327,0.0005298675,0.0003943169,0.00003694719,0.000006860319,0.00001590792,0.0001068047,0.00000673092,0.002069936],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001051201,"threshold_uncertainty_score":0.003516555,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02828740911172839,"score_gpt":0.2555793924364054,"score_spread":0.227291983324677,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}