{"id":"W4387462047","doi":"10.34172/bi.2023.27829","title":"Introduction of a new recombinant vaccine based on GRP78 for breast cancer immunotherapy and evaluation in a mouse model","year":2023,"lang":"en","type":"article","venue":"Bioimpacts","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"Isfahan University of Medical Sciences","keywords":"Immunotherapy; Breast cancer; Immune system; Medicine; Immunology; Cancer; Cancer immunotherapy; Cancer vaccine; Cytokine; Cancer research; Antibody; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001632308,0.00008022695,0.00009303511,0.00007086918,0.00001487656,0.000007446284,0.00003595609,0.00005214374,0.000009746716],"category_scores_gemma":[0.0000629818,0.00006819239,0.00003414607,0.00008229736,0.000009040114,0.000003512801,0.000009557657,0.0000209585,4.040819e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002049159,"about_ca_system_score_gemma":0.0001516282,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001182008,"about_ca_topic_score_gemma":0.00004988947,"domain_scores_codex":[0.9994652,0.00002073792,0.0001179776,0.0001861677,0.00008440739,0.0001255564],"domain_scores_gemma":[0.9996727,0.00000606771,0.00005320718,0.0001553676,0.00005562732,0.00005705961],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.002219612,0.0001512743,0.004022,0.00006540545,0.00002799911,3.108047e-7,0.00006952207,0.04164466,0.8963903,0.00003004926,0.0165415,0.03883732],"study_design_scores_gemma":[0.009660341,0.0007000131,0.08005317,0.00007048082,0.00004122044,0.000002296399,0.00005352853,0.5462662,0.3614272,0.0004549159,0.0009897503,0.0002808649],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973284,0.0002489073,0.0002642479,0.001620945,0.00007651247,0.0003261045,0.000114679,0.000009957517,0.00001026898],"genre_scores_gemma":[0.9987327,0.000486706,0.0001367696,0.00009944377,0.000110609,0.0000545728,0.0001242001,0.00001673653,0.0002382937],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5349631,"threshold_uncertainty_score":0.2780805,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01923142526812324,"score_gpt":0.3062603434213226,"score_spread":0.2870289181531994,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}