{"id":"W4387462047","doi":"10.34172/bi.2023.27829","title":"Introduction of a new recombinant vaccine based on GRP78 for breast cancer immunotherapy and evaluation in a mouse model","year":2023,"lang":"en","type":"article","venue":"Bioimpacts","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre","funders":"Isfahan University of Medical Sciences","keywords":"Immunotherapy; Breast cancer; Immune system; Medicine; Immunology; Cancer; Cancer immunotherapy; Cancer vaccine; Cytokine; Cancer research; Antibody; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005202269,0.001022698,0.0006655783,0.0009157342,0.0001959529,0.0004033294,0.0005158893,0.00105642,0.001498201],"category_scores_gemma":[0.0001822381,0.000231798,0.0005660696,0.0002863838,0.0004844024,0.0006057601,0.0001965995,0.001709537,0.0006222255],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003271845,"about_ca_system_score_gemma":0.0003387803,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002845587,"about_ca_topic_score_gemma":0.0002474663,"domain_scores_codex":[0.9995924,0.00006112436,0.00003850898,0.00009974315,0.0001099415,0.00009830931],"domain_scores_gemma":[0.9997846,0.00002708465,0.00005867942,0.00003733492,0.00003721222,0.00005515419],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004906307,0.0004661236,0.0001222305,0.0001286375,0.00001568541,0.00005336985,0.00002156631,0.0002037157,0.995077,0.0001865523,0.0001514656,0.003083185],"study_design_scores_gemma":[0.0001960265,0.006498047,0.0008186913,0.00002618032,0.00007232398,0.000295581,0.00002400934,0.001022323,0.9852539,0.0001163291,0.005664707,0.00001193141],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9680532,0.00449123,0.01941439,0.0009330967,0.0006696078,0.0008699666,0.002133589,0.0006730988,0.002761776],"genre_scores_gemma":[0.9525545,0.006466352,0.02703572,0.0004060596,0.0002089938,0.001664406,0.003411921,0.0001489103,0.008103304],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001498201,"threshold_uncertainty_score":0.005011976,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01923142526812324,"score_gpt":0.3062603434213226,"score_spread":0.2870289181531994,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}