{"id":"W4387477284","doi":"10.1016/j.jhazmat.2023.132749","title":"miR-20a-5p targeting mfn2-mediated mitochondria-lipid droplet contacts regulated differential changes in hepatic lipid metabolism induced by two Mn sources in yellow catfish","year":2023,"lang":"en","type":"article","venue":"Journal of Hazardous Materials","topic":"Environmental Toxicology and Ecotoxicology","field":"Environmental Science","cited_by":16,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University","funders":"Fundamental Research Funds for the Central Universities; National Key Research and Development Program of China","keywords":"Lipid metabolism; Lipid droplet; MFN2; Mitochondrion; Metabolism; Catfish; Toxicity; Chemistry; Cell biology; Pollutant; Biophysics; Biology; Biochemistry; Environmental chemistry; Ecology; Fish <Actinopterygii>; Gene; mitochondrial fusion; Mitochondrial DNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001891122,0.0003059871,0.0003821935,0.0001912912,0.0003374487,0.0004108045,0.0002449032,0.0004530088,0.001638225],"category_scores_gemma":[0.0001945414,0.0002693605,0.0003875842,0.0001168271,0.0004167872,0.000369826,0.0003460975,0.0007734376,0.0003825564],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004477218,"about_ca_system_score_gemma":0.0004118124,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002501487,"about_ca_topic_score_gemma":0.004255959,"domain_scores_codex":[0.9997026,0.00001858358,0.00002442847,0.0001247625,0.00006078833,0.00006878781],"domain_scores_gemma":[0.9999232,0.000009882637,0.00002101619,0.000006792839,0.00001483883,0.00002433231],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004679469,0.0000304231,0.0005468542,0.0001014455,0.00001195813,0.00007108912,0.00005740432,0.00009517965,0.9964695,0.0003044895,0.0001791527,0.001664542],"study_design_scores_gemma":[0.00008975552,0.0003102801,0.01165969,0.00001859482,0.00009937504,0.0002337712,0.0001598778,0.003295953,0.9736593,0.0001988945,0.01025322,0.00002124047],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9875875,0.00246296,0.005125327,0.0002917963,0.0002489884,0.00005046258,0.0008408285,0.0002163742,0.003175644],"genre_scores_gemma":[0.9893454,0.0005996437,0.002832788,0.0001851166,0.00001658203,0.00009892989,0.0005188316,0.00004836249,0.006354306],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002501487,"threshold_uncertainty_score":0.005480409,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009946997949916577,"score_gpt":0.2298308728861306,"score_spread":0.2198838749362141,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}