{"id":"W4387497202","doi":"10.1016/j.mcpro.2023.100660","title":"Proteomic and Phosphoproteomic Reprogramming in Epithelial Ovarian Cancer Metastasis","year":2023,"lang":"en","type":"article","venue":"Molecular & Cellular Proteomics","topic":"Microtubule and mitosis dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"London Health Sciences Centre; Western University","funders":"Canadian Institutes of Health Research; Ontario Ministry of Research and Innovation; Natural Sciences and Engineering Research Council of Canada; Ontario Ministry of Research, Innovation and Science","keywords":"Spheroid; ROCK1; Metastasis; Cancer research; Biology; Cell biology; Reprogramming; Cell; Cancer; Kinase; Cell culture; Protein kinase A; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0007014848,0.0004079913,0.0003764612,0.0002307313,0.0001319698,0.00009740549,0.0003479109,0.0003540523,0.00001779788],"category_scores_gemma":[0.00009992725,0.0004414176,0.0001790778,0.0005099103,0.0001363537,0.000012096,0.0004049439,0.0003186359,0.00003271202],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006331004,"about_ca_system_score_gemma":0.0001716604,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004563225,"about_ca_topic_score_gemma":0.00009282357,"domain_scores_codex":[0.9973928,0.0001572293,0.0004841663,0.001006073,0.0002220492,0.0007376554],"domain_scores_gemma":[0.9988791,0.000006235606,0.000163793,0.0007181255,0.00007025923,0.0001624835],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001219939,0.00005523811,0.002597877,0.00008036017,0.00009387173,0.0001033252,0.00009933621,0.0004079737,0.9897816,0.0001309043,0.00007315856,0.006454407],"study_design_scores_gemma":[0.001307003,0.0001327238,0.0009104389,0.00005419681,0.00004732976,0.00002384169,0.0000468265,0.001349801,0.9912742,0.0003301146,0.00400833,0.0005152321],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9886857,0.0009648912,0.007560606,0.0003295733,0.0001619912,0.002081372,0.0000622118,0.00007621178,0.00007750428],"genre_scores_gemma":[0.9843774,0.0008243209,0.01225163,0.0002523857,0.0001627295,0.001212128,0.00028056,0.0001433623,0.0004954821],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005939175,"threshold_uncertainty_score":0.9998038,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00844620111604691,"score_gpt":0.2410115680431696,"score_spread":0.2325653669271227,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}