{"id":"W4387519682","doi":"10.3389/fpsyt.2023.1234220","title":"BDNF gene Val66Met polymorphisms as a predictor for clinical presentation in schizophrenia – recent findings","year":2023,"lang":"en","type":"review","venue":"Frontiers in Psychiatry","topic":"Nerve injury and regeneration","field":"Neuroscience","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University; Providence Health Care","funders":"","keywords":"Schizophrenia (object-oriented programming); Endophenotype; Disease; Psychology; Web of science; Genotyping; Psychosis; Psychiatry; Meta-analysis; Bioinformatics; Clinical psychology; Medicine; Cognition; Gene; Genetics; Genotype; Internal medicine; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002139715,0.00042749,0.002084424,0.006669967,0.0002464872,0.001239844,0.0006428947,0.001010985,0.001786689],"category_scores_gemma":[0.0115166,0.0002921634,0.002460884,0.008549669,0.0003824917,0.0008733323,0.0004994527,0.000473023,0.0002108507],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007029069,"about_ca_system_score_gemma":0.002005946,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005748164,"about_ca_topic_score_gemma":0.01086547,"domain_scores_codex":[0.9981418,0.0003322848,0.0009185876,0.0002505626,0.000294493,0.00006228531],"domain_scores_gemma":[0.9856697,0.009692783,0.003480637,0.00009975032,0.0009217293,0.0001354276],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001368286,0.00008938972,0.08054646,0.6419121,0.00965957,0.002634032,0.001005501,0.0002946827,0.001577434,0.0004789658,0.006740612,0.253693],"study_design_scores_gemma":[0.0003202229,0.0007380983,0.3734278,0.4877702,0.0665972,0.01561339,0.00223294,0.0003793922,0.0007227489,0.001124617,0.05087354,0.0001997927],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.005873885,0.9931911,0.0000428858,0.0003055674,0.0000567361,0.00002429242,0.0002893027,0.0000022618,0.0002140394],"genre_scores_gemma":[0.05572153,0.9426175,0.0003422251,0.0004458454,0.0001876377,0.00007861035,0.0004999221,0.000003505125,0.0001031138],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.006669967,"threshold_uncertainty_score":0.01142937,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.126350117049447,"score_gpt":0.4227526220605869,"score_spread":0.2964025050111399,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}