{"id":"W4387524270","doi":"10.1016/j.jaip.2023.10.009","title":"Assessing Pediatric Cephalosporin Allergic Reactions Through Direct Graded Oral Challenges","year":2023,"lang":"en","type":"article","venue":"The Journal of Allergy and Clinical Immunology In Practice","topic":"Drug-Induced Adverse Reactions","field":"Medicine","cited_by":14,"is_retracted":false,"has_abstract":false,"ca_institutions":"Montreal General Hospital; Hospital for Sick Children; Children's Hospital Research Institute of Manitoba; Memorial University of Newfoundland; McGill University Health Centre; University of Toronto; Montreal Children's Hospital","funders":"Canadian Institutes of Health Research","keywords":"Medicine; Cephalosporin; Antibiotics; Allergic reaction; Cephalosporin Antibiotic; Intensive care medicine; Allergy; Dermatology; Microbiology; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003695177,0.0001762238,0.000554543,0.0002367272,0.0001904564,0.00002453162,0.0001960931,0.0003108344,0.00001481424],"category_scores_gemma":[0.004836354,0.0001224368,0.0001791558,0.0005857736,0.0002600176,0.001154075,0.0001060424,0.002142439,0.00006844344],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007061609,"about_ca_system_score_gemma":0.0002671337,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009644939,"about_ca_topic_score_gemma":0.00005728829,"domain_scores_codex":[0.9968643,0.0012089,0.001128362,0.0002058504,0.0002674679,0.000325141],"domain_scores_gemma":[0.9914902,0.00686694,0.0009548365,0.0003386317,0.0002523146,0.0000970129],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.01770211,0.03610344,0.02721039,0.0003880723,0.1229367,0.02343434,0.03157679,0.001953269,0.01791614,0.04495533,0.006640033,0.6691834],"study_design_scores_gemma":[0.005689341,0.0008473092,0.7830411,0.0001997711,0.003287443,0.007148176,0.0322453,0.00006275259,0.00006640117,0.002244504,0.1648688,0.0002990871],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9169726,0.008552899,0.00001486954,0.04129968,0.00205068,0.0001742541,7.057881e-7,0.00007598916,0.03085837],"genre_scores_gemma":[0.6339473,0.3644406,0.0004430365,0.0003060349,0.0004328826,0.000002797151,0.000001957902,0.00002162385,0.0004037062],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7558307,"threshold_uncertainty_score":0.9307952,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1338290960879485,"score_gpt":0.4339518907709275,"score_spread":0.300122794682979,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}