{"id":"W4387543122","doi":"10.1161/hyp.80.suppl_1.p312","title":"Abstract P312: Three-Month Human Endothelin-1 Endothelial Overexpression Up-Regulated <i>Khdrbs3</i> And Caused <i>Vegfa</i> And <i>Nrp2</i> Alternative Splicing In Mesenteric Arteries Of Male Mice","year":2023,"lang":"en","type":"article","venue":"Hypertension","topic":"Nitric Oxide and Endothelin Effects","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire Sainte-Justine; Jewish General Hospital","funders":"","keywords":"Alternative splicing; Exon; Endothelin 1; Biology; Tamoxifen; Molecular biology; Vascular endothelial growth factor A; Gene; Vascular endothelial growth factor; Endocrinology; Cancer research; Receptor; Genetics; Cancer; VEGF receptors","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002223843,0.0005060018,0.0003552724,0.0003307683,0.0003063701,0.0003347774,0.000252965,0.0004227744,0.004631379],"category_scores_gemma":[0.0001145853,0.000237798,0.0004199246,0.0002793891,0.0004475969,0.0003123578,0.0002248685,0.00110058,0.001306995],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003585306,"about_ca_system_score_gemma":0.000220643,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000564763,"about_ca_topic_score_gemma":0.0009776922,"domain_scores_codex":[0.9996328,0.00003332902,0.00003595521,0.0001436813,0.00008101496,0.00007307361],"domain_scores_gemma":[0.9997982,0.00002050735,0.00006155137,0.00002398238,0.00001957161,0.00007624328],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001306921,0.00002427768,0.00007866224,0.00001941837,0.000003032265,0.00004075316,0.00000789825,0.00001091795,0.999221,0.00003407188,0.00007316481,0.0003562184],"study_design_scores_gemma":[0.00004426082,0.0003518134,0.005839816,0.000006305154,0.00002159783,0.0004433676,0.00002997557,0.0002893516,0.9896277,0.0000391656,0.003299657,0.000006988348],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9819092,0.0008157272,0.008988956,0.0002908981,0.000153975,0.000101411,0.004957926,0.0003497362,0.002432398],"genre_scores_gemma":[0.9520762,0.0009490151,0.00971463,0.0003150689,0.00005868463,0.0003919234,0.01077041,0.0003132712,0.02541077],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004631379,"threshold_uncertainty_score":0.01549345,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02633321310849132,"score_gpt":0.2647735823989603,"score_spread":0.2384403692904689,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}