{"id":"W4387569295","doi":"10.3390/cancers15204956","title":"Nuclear Import and Export of YAP and TAZ","year":2023,"lang":"en","type":"review","venue":"Cancers","topic":"Hippo pathway signaling and YAP/TAZ","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; University of Toronto; Kidney Foundation of Canada","keywords":"Nuclear transport; Nuclear export signal; NLS; Nuclear localization sequence; Cell biology; Nuclear pore; Hippo signaling pathway; Transcription factor; Biology; PDZ domain; Cytoskeleton; Signal transduction; Cell nucleus; Nucleus; Gene; Genetics; Cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001475975,0.0001925166,0.0005686383,0.00004563651,0.00003484227,0.000009646753,0.0001009659,0.0002570986,0.00001826095],"category_scores_gemma":[0.00002678067,0.0001702706,0.0001233059,0.00007251393,0.0001178081,0.000001033227,0.0000890902,0.0001013981,0.000005002123],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000350617,"about_ca_system_score_gemma":0.0004405641,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002642033,"about_ca_topic_score_gemma":0.00000827335,"domain_scores_codex":[0.9991391,0.00002727744,0.0002619598,0.0003441103,0.00007235921,0.0001551429],"domain_scores_gemma":[0.9994717,0.0000097783,0.0001685568,0.0002373589,0.00002407781,0.00008856419],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003401465,0.00001307644,0.00006375013,0.03075081,0.0008905968,0.00006210913,0.0002029558,0.000003005231,0.02979724,0.000112457,0.006515299,0.9315547],"study_design_scores_gemma":[0.0000844844,0.00009968499,0.000003701497,0.001274246,0.0001345885,0.00002448091,0.0000288352,0.00000173082,0.000284547,0.000006517692,0.9978713,0.0001858953],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01139918,0.9876245,0.00000213621,0.000002733878,0.0001321898,0.0001718622,0.0001040066,0.00001341387,0.0005499805],"genre_scores_gemma":[0.0006616319,0.9979402,0.00004015451,0.00002804188,0.0001720832,0.00002073531,0.0001151331,0.00005456413,0.0009674844],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.991356,"threshold_uncertainty_score":0.6943434,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04409416440786218,"score_gpt":0.3176365491888659,"score_spread":0.2735423847810037,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}