{"id":"W4387569295","doi":"10.3390/cancers15204956","title":"Nuclear Import and Export of YAP and TAZ","year":2023,"lang":"en","type":"review","venue":"Cancers","topic":"Hippo pathway signaling and YAP/TAZ","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; University of Toronto; Kidney Foundation of Canada","keywords":"Nuclear transport; Nuclear export signal; NLS; Nuclear localization sequence; Cell biology; Nuclear pore; Hippo signaling pathway; Transcription factor; Biology; PDZ domain; Cytoskeleton; Signal transduction; Cell nucleus; Nucleus; Gene; Genetics; Cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001256128,0.0003662153,0.0003768329,0.0003715956,0.0002019813,0.0005625423,0.0002247789,0.0002482131,0.001772429],"category_scores_gemma":[0.000126971,0.0001132154,0.0002571292,0.0003304724,0.0002016549,0.0005536265,0.0003316534,0.0004589785,0.000763814],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004014326,"about_ca_system_score_gemma":0.0005055105,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006238581,"about_ca_topic_score_gemma":0.0009098648,"domain_scores_codex":[0.9999366,0.000006418794,0.000008839582,0.00001704269,0.00001799292,0.00001316486],"domain_scores_gemma":[0.9999608,0.000006321579,0.00001300766,0.000002172864,0.00001185998,0.000005953408],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007985946,0.00005813254,0.001359679,0.01570119,0.0001636466,0.002188568,0.0005685454,0.001490421,0.5332727,0.03227362,0.01484935,0.3972755],"study_design_scores_gemma":[0.00003800638,0.000297151,0.007929677,0.0004965013,0.0001298412,0.003320253,0.0002834038,0.001137198,0.1539082,0.003829027,0.8285841,0.00004664418],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.06598081,0.8985956,0.01085629,0.001931273,0.0007197142,0.00006765788,0.001684888,0.000312219,0.0198515],"genre_scores_gemma":[0.2158389,0.7579224,0.004280724,0.0004802388,0.0005736173,0.0001021419,0.002317034,0.00005007764,0.01843498],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001772429,"threshold_uncertainty_score":0.00592941,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04409416440786218,"score_gpt":0.3176365491888659,"score_spread":0.2735423847810037,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}