{"id":"W4387589984","doi":"10.1016/j.ijrobp.2023.08.027","title":"5-Year Outcomes from PACE B: An International Phase III Randomized Controlled Trial Comparing Stereotactic Body Radiotherapy (SBRT) vs. Conventionally Fractionated or Moderately Hypo Fractionated External Beam Radiotherapy for Localized Prostate Cancer","year":2023,"lang":"en","type":"article","venue":"International Journal of Radiation Oncology*Biology*Physics","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":51,"is_retracted":false,"has_abstract":false,"ca_institutions":"Health Sciences Centre; Sunnybrook Health Science Centre","funders":"","keywords":"Medicine; Prostate cancer; Randomized controlled trial; Clinical endpoint; Radiation therapy; External beam radiotherapy; Androgen deprivation therapy; Hazard ratio; Nuclear medicine; Urology; Radiosurgery; Cancer; Prostate; Dose fractionation; Surgery; Internal medicine; Confidence interval","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001783696,0.0004843026,0.002456935,0.0006373532,0.0002300364,0.0001852298,0.0005334616,0.0003599573,0.001024468],"category_scores_gemma":[0.0007758732,0.000345796,0.000969498,0.000328014,0.0003139393,0.0009554343,0.0000445225,0.0007098036,0.00001689104],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002146925,"about_ca_system_score_gemma":0.001859076,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001522849,"about_ca_topic_score_gemma":0.00001097978,"domain_scores_codex":[0.9952826,0.0007237254,0.001999654,0.0005605747,0.000959792,0.0004736668],"domain_scores_gemma":[0.991959,0.002841794,0.002415336,0.0002324459,0.002248581,0.0003028196],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9297769,0.002307763,0.0302908,0.00001139604,0.01201625,0.0001004114,0.0005359462,0.002371706,0.007301746,0.0006044533,0.0009337179,0.01374888],"study_design_scores_gemma":[0.8584619,0.002718662,0.004551672,0.00009980958,0.0005558369,0.00004913379,0.00009292921,0.1223971,0.0009729668,0.002144568,0.007653804,0.0003016606],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9528596,0.00101515,0.02537307,0.00665066,0.008362728,0.005011008,0.0004659225,0.0001783015,0.00008352984],"genre_scores_gemma":[0.9752145,0.01074657,0.003081159,0.00130062,0.004816633,0.001286743,0.002072168,0.0001163097,0.001365304],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1200254,"threshold_uncertainty_score":0.9998994,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04820762537308639,"score_gpt":0.4247409801308115,"score_spread":0.3765333547577251,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}