{"id":"W4387589985","doi":"10.1016/j.ijrobp.2023.08.025","title":"Randomized Phase III Trial of Postoperative Radiotherapy with or without Cetuximab for Intermediate-Risk Squamous Cell Carcinoma of the Head and Neck (SCCHN): NRG/RTOG 0920","year":2023,"lang":"en","type":"article","venue":"International Journal of Radiation Oncology*Biology*Physics","topic":"Head and Neck Cancer Studies","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; Université de Montréal; Centre Hospitalier de l’Université de Montréal","funders":"","keywords":"Medicine; Cetuximab; Clinical endpoint; Head and neck cancer; Hazard ratio; Internal medicine; Randomized controlled trial; Oncology; Radiation therapy; Exact test; Head and neck squamous-cell carcinoma; Toxicity; Log-rank test; Confidence interval; Cancer; Survival analysis; Colorectal cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001620824,0.001854308,0.002590254,0.000352743,0.0004768962,0.001173919,0.001413611,0.001452233,0.01283538],"category_scores_gemma":[0.001362519,0.0007527127,0.001744741,0.0004296409,0.00131601,0.001195032,0.0005575207,0.003623928,0.002243327],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001170825,"about_ca_system_score_gemma":0.001841313,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003102821,"about_ca_topic_score_gemma":0.009139834,"domain_scores_codex":[0.9995592,0.000211466,0.00002031341,0.0001008704,0.0000283971,0.00007982795],"domain_scores_gemma":[0.9993598,0.0001516566,0.0001191488,0.00006742751,0.00003648027,0.0002654992],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9708136,0.007147525,0.0004560339,0.0004247219,0.0008741796,0.0000236538,0.00005125575,0.000604729,0.002682479,0.0002044168,0.001847647,0.01486967],"study_design_scores_gemma":[0.9608932,0.03621558,0.001032671,0.00002270327,0.0003536384,0.00002203132,0.00002974916,0.0003440763,0.0002404638,0.0001559362,0.0006778445,0.00001209404],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9829578,0.003389435,0.0007614315,0.001214587,0.001190432,0.003376923,0.00214571,0.0002323021,0.004731399],"genre_scores_gemma":[0.9747371,0.002623795,0.002322322,0.002346472,0.0003795557,0.004526162,0.002746075,0.0000828605,0.01023563],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01283538,"threshold_uncertainty_score":0.04293865,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0263538953786217,"score_gpt":0.3618704264672269,"score_spread":0.3355165310886052,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}