{"id":"W4387621189","doi":"10.1161/res.133.suppl_1.p1183","title":"Abstract P1183: Phosphorylation Signatures Of Human Heart Failure: Characterizing Dilated Cardiomyopathy-associated Signaling Pathways At The Cardiomyocyte Intercalated Disc","year":2023,"lang":"en","type":"article","venue":"Circulation Research","topic":"Cardiomyopathy and Myosin Studies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; York University; University of Toronto","funders":"","keywords":"Intercalated disc; Dilated cardiomyopathy; Heart failure; Phosphorylation; Cardiomyopathy; Ischemic cardiomyopathy; Biology; Myocardial infarction; Internal medicine; Ventricular remodeling; Medicine; Cell biology; Cardiology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003757687,0.0002749514,0.0007214575,0.00058901,0.001015203,0.00009209852,0.0001858044,0.0002867142,0.0001016445],"category_scores_gemma":[0.0007521777,0.0002180064,0.0004909665,0.002249756,0.0003612403,0.0001816542,0.0003070105,0.0008423348,0.0001119995],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004786275,"about_ca_system_score_gemma":0.000133778,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002386483,"about_ca_topic_score_gemma":0.00004032883,"domain_scores_codex":[0.9960559,0.0004626317,0.0007002722,0.0005601657,0.001515095,0.0007059568],"domain_scores_gemma":[0.997374,0.0006207002,0.0002091703,0.0006188233,0.001023305,0.0001540175],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0001751871,0.00006131014,0.05538329,0.000158765,0.0004583744,0.00005928131,0.002239684,0.00159369,0.9359238,0.00007026011,0.002839228,0.001037162],"study_design_scores_gemma":[0.001131993,0.0001142427,0.9352717,0.000417723,0.0001278129,0.00001607584,0.001300356,0.001111695,0.05906449,0.0001456742,0.001068315,0.0002299059],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953344,0.0007182916,0.00002156642,0.001173322,0.0002247763,0.001119337,0.00007061538,0.0002713488,0.001066302],"genre_scores_gemma":[0.9984402,0.00006262853,0.000006649062,0.00004984413,0.0002415802,0.0001095866,0.0007806589,0.00006378435,0.0002450743],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8798884,"threshold_uncertainty_score":0.8890044,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07970236589820334,"score_gpt":0.3495927963664442,"score_spread":0.2698904304682409,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}