{"id":"W4387670530","doi":"10.3390/antiox12101867","title":"N-Acetylcysteine and Its Immunomodulatory Properties in Humans and Domesticated Animals","year":2023,"lang":"en","type":"review","venue":"Antioxidants","topic":"Sulfur Compounds in Biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":43,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph","funders":"","keywords":"Acetylcysteine; Antioxidant; Oxidative stress; Antidote; Pharmacology; Glutathione; Cysteine; Tumor necrosis factor alpha; Antimicrobial; Mucin; Medicine; Chemistry; Biology; Microbiology; Immunology; Biochemistry; Toxicity; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002645756,0.00060921,0.0007754933,0.001658991,0.0002248762,0.0005478499,0.0004298976,0.0006240457,0.002180748],"category_scores_gemma":[0.0003151562,0.0001972157,0.0003075958,0.001323329,0.0002854592,0.0007400125,0.0004359924,0.001036333,0.0009324552],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003727777,"about_ca_system_score_gemma":0.0005935212,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001080744,"about_ca_topic_score_gemma":0.001887991,"domain_scores_codex":[0.9999021,0.00001628649,0.00002013884,0.00001936935,0.00003259682,0.00000947692],"domain_scores_gemma":[0.9998987,0.00004218843,0.00001775233,0.000003118769,0.00002825313,0.00001001656],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001181316,0.00009254555,0.0002514225,0.02165112,0.00009767416,0.0002895608,0.00008883441,0.0002580427,0.005576059,0.002946117,0.01722263,0.9514079],"study_design_scores_gemma":[0.0000137404,0.0001523434,0.001576035,0.002287344,0.0001167774,0.001467659,0.00005109221,0.00006166683,0.001260274,0.001152979,0.9918427,0.00001743206],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001898971,0.9989172,0.000063686,0.0000925927,0.00009167067,0.000002787001,0.00001282922,0.000004356342,0.0006250324],"genre_scores_gemma":[0.0009767781,0.998085,0.0001415366,0.00009548792,0.00009498857,0.000005347906,0.00002938377,0.00000103896,0.0005704812],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002180748,"threshold_uncertainty_score":0.00729537,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08075959184117691,"score_gpt":0.3361591951757896,"score_spread":0.2553996033346126,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}