{"id":"W4387683627","doi":"10.1016/j.yjmcc.2023.10.001","title":"Loss of TIMP3, but not TIMP4, exacerbates thoracic and abdominal aortic aneurysm","year":2023,"lang":"en","type":"article","venue":"Journal of Molecular and Cellular Cardiology","topic":"Aortic aneurysm repair treatments","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"Alberta Hospital Edmonton; University of Alberta Hospital; University of Alberta","funders":"Institute of Circulatory and Respiratory Health; Canadian Institutes of Health Research; China Scholarship Council; Canada Research Chairs; Heart and Stroke Foundation of Canada","keywords":"Medicine; Inflammation; Adventitia; Abdominal aortic aneurysm; Tissue inhibitor of metalloproteinase; Internal medicine; Pathology; Aortic aneurysm; Aorta; Matrix metalloproteinase; Elastin; Endocrinology; Cardiology; Aneurysm; Surgery","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002814726,0.0004772523,0.0004559944,0.0002792972,0.0002798055,0.0005232468,0.0002442959,0.0005490358,0.003815782],"category_scores_gemma":[0.0004051725,0.0002259073,0.000548051,0.0002059029,0.0003649523,0.0002391944,0.0003149579,0.001400703,0.0005650799],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002546383,"about_ca_system_score_gemma":0.0004498216,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004257309,"about_ca_topic_score_gemma":0.000703832,"domain_scores_codex":[0.9996616,0.00006448491,0.00002546717,0.00003997465,0.00007386416,0.0001345946],"domain_scores_gemma":[0.9995957,0.00003466496,0.000169567,0.00002660449,0.00002476859,0.0001486405],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004834621,0.0004391973,0.009562651,0.0002661533,0.0001674136,0.001449877,0.00007416165,0.0002558661,0.9702021,0.0003313674,0.0009904051,0.01142618],"study_design_scores_gemma":[0.0007052844,0.01241507,0.4407678,0.000211529,0.001181175,0.0162774,0.001464381,0.003231712,0.5022287,0.001866394,0.01953982,0.0001107435],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943601,0.002056907,0.000990847,0.0004551112,0.0001497988,0.00001646686,0.0002888234,0.00008480104,0.001597049],"genre_scores_gemma":[0.9958044,0.001125444,0.0005774746,0.0002321071,0.00008486883,0.00002691284,0.0002476899,0.00001814176,0.001883131],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003815782,"threshold_uncertainty_score":0.01276505,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01327042315731745,"score_gpt":0.2714068103691951,"score_spread":0.2581363872118776,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}