{"id":"W4387692396","doi":"10.1111/ene.16101","title":"Progression of brain cholinergic dysfunction in patients with isolated rapid eye movement sleep behavior disorder","year":2023,"lang":"en","type":"article","venue":"European Journal of Neurology","topic":"Sleep and Wakefulness Research","field":"Neuroscience","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Instituto de Salud Carlos III; Danmarks Frie Forskningsfond","keywords":"Donepezil; Statistical parametric mapping; Montreal Cognitive Assessment; Medicine; REM sleep behavior disorder; Rapid eye movement sleep; Cognition; Internal medicine; Cognitive decline; Cardiology; Audiology; Effects of sleep deprivation on cognitive performance; Psychology; Eye movement; Psychiatry; Parkinson's disease; Dementia; Disease; Magnetic resonance imaging; Ophthalmology; Radiology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002397303,0.0003195958,0.000481976,0.0004739544,0.0003372928,0.00042425,0.0001990908,0.0003353885,0.0009342039],"category_scores_gemma":[0.0007847086,0.0001368381,0.0002793758,0.0003571689,0.0001840029,0.0002410693,0.0001939704,0.0004396306,0.00018185],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002623008,"about_ca_system_score_gemma":0.0001963191,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003553482,"about_ca_topic_score_gemma":0.004595724,"domain_scores_codex":[0.9999099,0.00001583414,0.00001182859,0.00002681255,0.00001976306,0.00001590173],"domain_scores_gemma":[0.9996496,0.00006454197,0.0001445709,0.00001800401,0.00006196815,0.00006132534],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0007565758,0.0000901401,0.9900975,0.00002505895,0.00006753417,0.0009591146,0.0001199563,0.0000772851,0.002172077,0.000008565878,0.00007684663,0.005549416],"study_design_scores_gemma":[0.00002422465,0.0003401243,0.9972321,0.000005443479,0.00004015276,0.001825528,0.00008848949,0.0001545874,0.0001948107,0.00001855904,0.00007316983,0.000002870657],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992658,0.0002606788,0.00004767041,0.00001776868,0.000002769191,0.00000661065,0.00008048737,0.000004754158,0.000313457],"genre_scores_gemma":[0.9997259,0.00005804738,0.0000374267,0.00001129412,0.000004505212,0.000003007955,0.00009874248,6.076123e-7,0.00006047692],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003553482,"threshold_uncertainty_score":0.007065594,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0189198467393894,"score_gpt":0.2779316381363444,"score_spread":0.259011791396955,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}