{"id":"W4387692608","doi":"10.1007/s00428-023-03673-9","title":"Evaluation of an institutional series of low-grade oncocytic tumor (LOT) of the kidney and review of the mutational landscape of LOT","year":2023,"lang":"en","type":"review","venue":"Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin","topic":"Renal cell carcinoma treatment","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Calgary Laboratory Services; University of Calgary","funders":"","keywords":"TSC1; Eosinophilic; TFE3; Biology; Pathology; Cohort; Immunohistochemistry; Medicine; Internal medicine; PI3K/AKT/mTOR pathway; Gene; Genetics; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000844881,0.0002424648,0.0002361113,0.004891158,0.0003960395,0.0006344235,0.0004658137,0.0003163721,0.0006965648],"category_scores_gemma":[0.003265521,0.0002313271,0.000267753,0.002419641,0.0005770609,0.0005198751,0.0003989276,0.0001897574,0.0003307346],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004428561,"about_ca_system_score_gemma":0.000517304,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008907562,"about_ca_topic_score_gemma":0.001571885,"domain_scores_codex":[0.9993495,0.0001159552,0.0002410669,0.0001019614,0.0001353185,0.0000560357],"domain_scores_gemma":[0.9972194,0.001148989,0.0006703648,0.0002467374,0.0005138287,0.0002006849],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001461126,0.0000482308,0.9078516,0.0007305875,0.0001133635,0.04190435,0.0006757132,0.0001633442,0.006022573,0.0001783137,0.001065307,0.04110029],"study_design_scores_gemma":[0.00001307471,0.0002236839,0.7920333,0.0003104278,0.0001754386,0.1927464,0.001162733,0.0002528094,0.004674552,0.0001118915,0.008265126,0.00003050116],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"review","genre_scores_codex":[0.9812658,0.01451679,0.001066232,0.0001097941,0.00003180121,0.00005384384,0.0004576831,0.00003914829,0.002458875],"genre_scores_gemma":[0.988425,0.009206264,0.001062512,0.0001123693,0.00007961661,0.00003055449,0.0007302245,0.00001240405,0.0003410376],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.004891158,"threshold_uncertainty_score":0.004468203,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1088134030194649,"score_gpt":0.4132176206336188,"score_spread":0.3044042176141539,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}