{"id":"W4387693423","doi":"10.1016/s2214-109x(23)00421-7","title":"Clinical and regulatory development strategies for Shigella vaccines intended for children younger than 5 years in low-income and middle-income countries","year":2023,"lang":"en","type":"review","venue":"The Lancet Global Health","topic":"Viral gastroenteritis research and epidemiology","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre for Global Health Research","funders":"European Medicines Agency; World Health Organization; Bill and Melinda Gates Foundation","keywords":"Shigellosis; Low and middle income countries; Medicine; Environmental health; Population; Public health; Clinical trial; Shigella; Developing country; Economic growth; Nursing; Salmonella; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006727707,0.0008648183,0.001526692,0.002386613,0.0003125544,0.001997047,0.001776701,0.002643225,0.005523792],"category_scores_gemma":[0.00637563,0.0003943788,0.001323362,0.001786322,0.0008723601,0.002469265,0.001044118,0.002732435,0.001711639],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001399751,"about_ca_system_score_gemma":0.005686082,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001899515,"about_ca_topic_score_gemma":0.002810483,"domain_scores_codex":[0.998478,0.0006071031,0.0002137071,0.000128078,0.0004296442,0.0001435304],"domain_scores_gemma":[0.9966138,0.001826425,0.0005364187,0.00008746269,0.000778208,0.0001577008],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001483925,0.00007236309,0.0001678637,0.04382797,0.0001655345,0.0001453915,0.0001501096,0.0004703196,0.0009922259,0.01286162,0.04807631,0.8929219],"study_design_scores_gemma":[0.00009155919,0.0001453971,0.0006142308,0.0267935,0.000242089,0.000285998,0.0001050434,0.00007472814,0.0003875941,0.003379936,0.9678606,0.00001926077],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001074955,0.9961993,0.0001755327,0.001691338,0.0004330004,0.00003552633,0.00003225299,0.00001002175,0.001315584],"genre_scores_gemma":[0.001174116,0.9959921,0.000501288,0.001474364,0.0002144577,0.00006252839,0.00004999172,0.000003076995,0.0005279669],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.006727707,"threshold_uncertainty_score":0.03557998,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1319180102644675,"score_gpt":0.4679109884957281,"score_spread":0.3359929782312606,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}