{"id":"W4387728795","doi":"10.1176/appi.ajp.20230053","title":"Meta-Analyses of Genome-Wide Association Studies for Postpartum Depression","year":2023,"lang":"en","type":"article","venue":"American Journal of Psychiatry","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":66,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Health and Medical Research Council; Horizon 2020 Framework Programme; Norges Forskningsråd; H. Lundbeck A/S; National Institute of Mental Health; Vetenskapsrådet; Lundbeckfonden; Wellcome Trust; National Institutes of Health; Sage Therapeutics; National Alliance for Research on Schizophrenia and Depression; Helse Sør-Øst RHF; Medical Research Council; Biogen; Women's College Hospital; European Commission; Bill and Melinda Gates Foundation","keywords":"Depression (economics); Genome-wide association study; Postpartum depression; Association (psychology); Genetic association; Psychology; Psychiatry; Meta-analysis; Medicine; Clinical psychology; Genetics; Biology; Pregnancy; Internal medicine; Single-nucleotide polymorphism; Psychotherapist; Genotype; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009613614,0.0001060122,0.0005880969,0.0001087662,0.00005760651,0.000004081503,0.0001486562,0.00006054963,0.000006177254],"category_scores_gemma":[0.001637768,0.00007799573,0.0005440676,0.0002130364,0.00005853925,0.000003394155,0.00003951563,0.00006596875,0.000002150333],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002169772,"about_ca_system_score_gemma":0.0001134265,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009118631,"about_ca_topic_score_gemma":0.0000168377,"domain_scores_codex":[0.9987507,0.0001840105,0.0005947119,0.0001370997,0.0001450768,0.0001884417],"domain_scores_gemma":[0.9974172,0.0003703395,0.001558399,0.0001521337,0.0004513117,0.00005061026],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001415353,0.00007456771,0.8971765,0.00002756117,0.01515099,4.774844e-7,0.0001125587,0.002191417,0.02025433,0.00001608798,0.0640192,0.0008347576],"study_design_scores_gemma":[0.001152087,0.002952754,0.9608947,0.000025343,0.008098318,0.00001306532,0.004615152,0.00006991302,0.004959168,0.003752203,0.01312669,0.0003406161],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9842294,0.006168595,0.002891784,0.00604029,0.0005013031,0.00008519139,0.00003273928,0.000004317113,0.00004633536],"genre_scores_gemma":[0.982362,0.001727249,0.01441563,0.0007728157,0.0003484221,0.00001145692,0.00002822757,0.0000153008,0.0003189402],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06371818,"threshold_uncertainty_score":0.3180573,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07130023520137943,"score_gpt":0.3792025871312677,"score_spread":0.3079023519298882,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}