{"id":"W4387729182","doi":"10.1097/ypg.0000000000000353","title":"Chromatin gatekeeper and modifier CHD proteins in development, and in autism and other neurological disorders","year":2023,"lang":"en","type":"review","venue":"Psychiatric Genetics","topic":"Chromatin Remodeling and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria; University of Toronto; Centre for Addiction and Mental Health","funders":"","keywords":"Chromodomain; Chromatin; Epigenetics; Biology; Chromatin remodeling; ChIA-PET; Genetics; Histone; DNA methylation; PHD finger; Gene; Transcription factor; Computational biology; Cell biology; Helicase; Gene expression; RNA; Zinc finger","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001968502,0.0003268337,0.0005167615,0.0001595351,0.0000460611,0.00003097613,0.0001210574,0.000430246,0.00000313667],"category_scores_gemma":[0.00002429899,0.0002841485,0.0000512466,0.0002202514,0.00007367192,0.000001430277,0.0001766065,0.0002246848,0.00000321308],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001069819,"about_ca_system_score_gemma":0.0001523676,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002374498,"about_ca_topic_score_gemma":0.0005209626,"domain_scores_codex":[0.998414,0.00009913398,0.0004729515,0.0006220974,0.0001015862,0.0002901792],"domain_scores_gemma":[0.9995552,0.00002162228,0.0001249102,0.0002139786,0.000006390753,0.00007785824],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002083923,0.0001046106,0.004665473,0.007347366,0.00007183175,0.000005516631,0.0001868173,0.00005435056,0.00004518914,0.00002199426,0.000123379,0.9873526],"study_design_scores_gemma":[0.001444735,0.00027246,0.009311259,0.001346949,0.0001452538,0.00007034222,0.00003174143,0.0008297742,0.000010106,0.0005096556,0.9849263,0.001101432],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.1847127,0.814428,0.00003711294,0.00003766068,0.00008256423,0.000580343,0.00001489179,0.00001141837,0.00009528594],"genre_scores_gemma":[0.004311878,0.9928393,0.002352946,0.00007274316,0.00006948389,0.0001511534,0.00003040748,0.00006125429,0.0001108088],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9862512,"threshold_uncertainty_score":0.9999611,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03406662020432991,"score_gpt":0.3046225267244689,"score_spread":0.270555906520139,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}